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ProteomicsComprehensive characterization of Minichromosome Maintenance Complex (MCM) protein interactions using affinity and proximity purifications coupled to mass spectrometry.
This project is the complete interactome of the Minichromosome Maintenance (MCM) complex by using AP-MS and BioID approaches for all the different MCM proteins. Overall, our analysis identified unique and shared interaction partners and proteins enriched for distinct biological processes including D...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000080198 | MassIVE
ProteomicsComprehensive characterization of Minichromosome Maintenance Complex (MCM) protein interactions using affinity and proximity purifications coupled to mass spectrometry.
This project is the complete interactome of the Minichromosome Maintenance (MCM) complex by using AP-MS and BioID approaches for all the different MCM proteins. Overall, our analysis identified unique and shared interaction partners and proteins enriched for distinct biological processes including D...
ORGANISM(S): Homo sapiens (Human) 
2016-08-09 | PXD004089 | Pride
Ap-ms Bioid Mcm complex 
ProteomicsDestabilization of the MiniChromosome Maintenance (MCM) complex modulates the cellular response to DNA double strand breaks induced by Etoposide.
DNA replication during S phase involves thousands of replication forks that must be coordinated to ensure that every DNA section is only replicated once. The minichromosome maintenance proteins, MCM2 to MCM7, form a heteromeric DNA helicase required for both initiation of DNA replication and elongat...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD009539 | Pride
Dna repair Mcm protein Etoposide Dna damage Homologous recombination 
UnknownDNA induces conformational changes in a recombinant human minichromosome maintenance complex.
Not available
S-EPMC4367295 | biostudies-literature
UnknownThe minichromosome maintenance complex drives esophageal basal zone hyperplasia.
Not available
S-EPMC10544209 | biostudies-literature
UnknownThe minichromosome maintenance replicative helicase.
Not available
S-EPMC3809582 | biostudies-literature
GenomicsMating-induced DNA replication factor minichromosome maintenance protein 10 promotes oogenesis in Plutella xylostella
Mating-induced DNA replication factor minichromosome maintenance protein 10 promotes oogenesis in Plutella xylostella
PRJNA1283205 | ENA
UnknownHeterogeneous Expression Patterns of the Minichromosome Maintenance Complex Members in Retinoblastoma Unveil Its Clinical Significance.
Not available
S-EPMC10795548 | biostudies-literature
UnknownNovel protein contact points among TP53 and minichromosome maintenance complex proteins 2, 3, and 5.
Not available
S-EPMC9761056 | biostudies-literature
UnknownBI-2536 Promotes Neuroblastoma Cell Death via Minichromosome Maintenance Complex Components 2 and 10.
Not available
S-EPMC8778242 | biostudies-literature
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