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BACKGROUND AND HYPOTHESIS: It is presently unclear why there is a high prevalence of periodontal disease in individuals living with chronic kidney disease. Whilst some have argued that periodontal disease causes chronic kidney disease, we hypothesized that alterations in saliva ...

2025-09-04 | MTBLS1833 | MetaboLights
Objectives ELB-21 is a pyrrolo[2,1-c][1,4]benzodiazepine dimer with potent antistaphylococcal activity; it binds covalently to guanine residues on opposing strands of duplex DNA, interfering with regulatory proteins and transcription elongation in a sequence-selective manner. Transcriptional and pro...
ORGANISM(S): Staphylococcus aureus 
Transcriptome data from individual lck:GFP expressing cells isolated from spleens of two adult Zebrafish. LCK is a marker of lymphocytes and here we identified two major subpopulations corresponding to T-cells and NK-like and a minor one of myeloid-like cells. Single cell transcriptomes are matched ...
ORGANISM(S): Danio rerio 
The glucocorticoid receptor (GR) is a nuclear hormone receptor critical to the regulation of energy metabolism and the inflammatory response. The actions of GR have been shown to be highly dependent on context. Here, we demonstrate the necessity for liver lineage-determining factor hepatocyte nuclea...
ORGANISM(S): Mus musculus 
Saliva is composed of a variety of molecules that modulate the oral cavity. It is mainly composed of water (95%) and several minor components such as electrolytes, proteins, and low molecular weight compounds. It consists of metabolites from drinks, foods, drugs, environmental contaminants, and bact...
2015-09-01 | MTBLS100 | MetaboLights
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