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The Aryl Hydrocarbon Receptor (AHR) regulates the expression of numerous genes in response to activation by agonists including xenobiotics. Although it is well appreciated that environmental signals and cell intrinsic features may modulate this transcriptional response, how it is mechanistically ach...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD028992 | Pride
Background & Aims Obesity is a major risk factor for metabolic associated steatotic liver disease (MASLD) which can progress from metabolic associated steatotic liver (MASL) to metabolic associated steatohepatitis (MASH). There are currently no effective and validated screening tools to stratify obe...
ORGANISM(S): Homo sapiens (Human) 
2025-04-14 | PXD052798 | Pride
An approximate 1 cm3 wedge liver biopsy was collected from the left lobe of the liver during surgery. The liver was cut into two portions. One portion was placed in formalin and transported to TissuPathTM (Mount Waverley, Victoria), paraffin embedded and processed for histological analysis. Samples ...
ORGANISM(S): Homo sapiens (Human) 
2025-03-25 | PXD052787 | Pride
Background & Aims Obesity is a major risk factor for metabolic associated steatotic liver disease (MASLD) which can progress from metabolic associated steatotic liver (MASL) to metabolic associated steatohepatitis (MASH). There are currently no effective and validated screening tools to stratify obe...
ORGANISM(S): Homo sapiens (Human) 
2025-04-14 | PXD052784 | Pride
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