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MetabolomicsGNPS - Periphylla associated microbiota_2020
Extracts of selected microbial community associated with the mesopelagic Periphylla periphylla jellyfish
ORGANISM(S): Periphylla Periphylla (ncbitaxon:880221) 
2023-01-16 | MSV000091067 | GNPS
TranscriptomicsMYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
MYCN is a master regulator controlling many processes necessary for tumor cell survival. Here, we unravel a microRNA network that causes tumor suppressive effects in MYCN-amplified neuroblastoma cells. In profiling studies, histone deacetylase (HDAC) inhibitor treatment most strongly induced miR-183...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-44538 | biostudies-arrayexpress
TranscriptomicsHypermethylation of miR-34b is associated with CREB overexpression and Myeloid Cell Transformation
Increased CREB levels and upregulation of its target genes expression resulted in increased myelopoiesis and colony formation. Class comparison between MDS patients at diagnosis and evolution in AML
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-25300 | biostudies-arrayexpress
TranscriptomicsEffects of moderate ethanol consumption during pregnancy on placental gene expression
We conducted a preliminary investigation to determine whether ethanol-induced alterations in placental gene expression may have some utility as a diagnostic indicator of maternal drinking during pregnancy as well as a prognostic indicator of risk for adverse neurobehavioral outcomes in affected offs...
ORGANISM(S): Rattus norvegicus 
2010-02-21 | E-GEOD-18162 | biostudies-arrayexpress
TranscriptomicsA microRNA microarray analysis of C.elegans Parkinsons disease models
MicroRNAs (miRNAs) play an important role in human brain development and maintenance. To search for miRNAs potentially involved with molecular mechanisms in the pathogenesis of Parkinsons disease (PD), we utilized miRNA microarrays to identify expression changes of 115 annotated Caenorhabditis elega...
ORGANISM(S): Caenorhabditis elegans 
2010-06-20 | E-GEOD-14899 | biostudies-arrayexpress
TranscriptomicsReconstruction of microRNA/genes transcriptional regulatory networks of multiple myeloma through in silico integrative genomics analysis [MM, miRNA]
The identification of deregulated miRNA in multiple myeloma (MM) has progressively added a further level of complexity to MM biology. In the present study, we take virtue of in silico integrative genomics analysis to generate an unprecedented global view of the transcriptional regulatory networks mo...
ORGANISM(S): Homo sapiens 
2015-12-08 | E-GEOD-70254 | biostudies-arrayexpress
TranscriptomicsReconstruction of microRNA/genes transcriptional regulatory networks of multiple myeloma through in silico integrative genomics analysis [PCL, gene]
The identification of deregulated miRNA in multiple myeloma (MM) has progressively added a further level of complexity to MM biology. In the present study, we take virtue of in silico integrative genomics analysis to generate an unprecedented global view of the transcriptional regulatory networks mo...
ORGANISM(S): Homo sapiens 
2015-12-08 | E-GEOD-73452 | biostudies-arrayexpress
TranscriptomicsReconstruction of microRNA/genes transcriptional regulatory networks of multiple myeloma through in silico integrative genomics analysis [PCL, miRNA]
The identification of deregulated miRNA in multiple myeloma (MM) has progressively added a further level of complexity to MM biology. In the present study, we take virtue of in silico integrative genomics analysis to generate an unprecedented global view of the transcriptional regulatory networks mo...
ORGANISM(S): Homo sapiens 
2015-12-08 | E-GEOD-73454 | biostudies-arrayexpress
Transcriptomicsc-Myb inhibits myoblast fusion
The study of the effects of modification of c-Myb expression on differenatiation of C2C12 cells
ORGANISM(S): Mus musculus 
2013-10-21 | E-MTAB-1376 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of miRNA expression profile during Mycobacterium tuberculosis infection of human primary dendritic cells
Mycobacterium tuberculosis (Mtb) is one of the most successful pathogens in human history and remains the second leading cause of death from an infectious agent worldwide. The major reason of Mtb success principally relies on its ability to perfectly adapt to the host, by establishing latent infecti...
ORGANISM(S): Homo sapiens 
2017-12-12 | E-MTAB-6083 | biostudies-arrayexpress
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