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TranscriptomicsDynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis
We used mouse ENCODE data along with complementary data from other laboratories to study the dynamics of occupancy and the role in gene regulation of the transcription factor TAL1, a critical regulator of hematopoiesis, at multiple stages of hematopoietic differentiation. We combined ChIP-seq and RN...
ORGANISM(S): Mus musculus 
2014-11-14 | E-GEOD-51338 | biostudies-arrayexpress
GenomicsIdentification of Biologically Relevant Enhancers in Human Erythroid Cells [ChIP-Seq]
Identification of cell-type specific enhancers is important for understanding the regulation of programs controlling cellular development and differentiation. Enhancers are typically marked by the co-transcriptional activator protein p300 or by groups of cell-expressed transcription factors. We hypo...
ORGANISM(S): Homo sapiens 
2013-01-28 | E-GEOD-43625 | biostudies-arrayexpress
TranscriptomicsIdentification of Biologically Relevant Enhancers in Human Erythroid Cells [Illumina BeadArray]
Identification of cell-type specific enhancers is important for understanding the regulation of programs controlling cellular development and differentiation. Enhancers are typically marked by the co-transcriptional activator protein p300 or by groups of cell-expressed transcription factors. We hypo...
ORGANISM(S): Homo sapiens 
2013-01-28 | E-GEOD-43624 | biostudies-arrayexpress
TranscriptomicsDivergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis
Combinatorial actions of relatively few transcription factors control hematopoietic differentiation. To investigate this process in erythro-megakaryopoiesis, we correlated the genome-wide chromatin occupancy signatures of four master hematopoietic transcription factors (GATA1, GATA2, SCL/TAL1 and FL...
ORGANISM(S): Mus musculus 
2013-08-09 | E-GEOD-49664 | biostudies-arrayexpress
TranscriptomicsDivergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis
Combinatorial actions of relatively few transcription factors control hematopoietic differentiation. To investigate this process in erythro-megakaryopoiesis, we correlated the genome-wide chromatin occupancy signatures of four master hematopoietic transcription factors (GATA1, GATA2, TAL1, and FLI1)...
ORGANISM(S): Mus musculus 
2014-11-14 | E-GEOD-51337 | biostudies-arrayexpress
TranscriptomicsLong noncoding RNA expression in several hematopoietic progenitor and differentiated cell populations using a custom Agilent microarray
Mammals express thousands of long noncoding (lnc) RNAs, a few of which are shown to function in tissue development. However, the entire repertoire of lncRNAs and the extent to which they regulate biological processes in different tissues and species are not defined. Indeed, most lncRNAs are not cons...
ORGANISM(S): Mus musculus 
2014-02-20 | E-GEOD-51892 | biostudies-arrayexpress
GenomicsGenome-wide maps of epigenetic features in G1E model and in mouse primary erythroblasts.
Interplays among lineage specific nuclear proteins, chromatin modifying enzymes and the basal transcription machinery govern cellular differentiation, but their dynamics of actions and coordination with transcriptional control are not fully understood. Alterations in chromatin structure appear to es...
ORGANISM(S): Mus musculus 
2011-07-05 | E-GEOD-30142 | biostudies-arrayexpress
ProteomicsTargeted and non-targeted mass spectrometry to explore the chemical diversity of the genus Gambierdiscus in the Atlantic Ocean
The 15 strains of Gambierdiscus were cultivated in four separate laboratories. Each laboratory grew their available strains (see sample metadata) in addition to the G. australes strain AUS S080911_1 isolated from Pacific Ocean. Irradiance (70-100 umol photons m-2 s-1) and light/dark cycle (12h:12h)...
ORGANISM(S): Gambierdiscus Silvae (ncbitaxon:1550089) Gambierdiscus Carolinianus (ncbitaxon:864182) Gambierdiscus Australes (ncbitaxon:439317) Gambierdiscus Belizeanus (ncbitaxon:439316) Gambierdiscus Excentricus (ncbitaxon:986170) Gambierdiscus Caribaeus (ncbitaxon:864185) 
2024-02-26 | MSV000094172 | MassIVE
UnknownDisease Characteristics, Care-Seeking Behavior, and Outcomes Associated With the Use of AYUSH-64 in COVID-19 Patients in Home Isolation in India: A Community-Based Cross-Sectional Analysis.
Not available
S-EPMC9310753 | biostudies-literature
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