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TranscriptomicsDNA methylation programming and reprogramming in primate embryonic stem cells
DNA methylation is an important epigenetic mechanism, affecting normal development and playing a key role in reprogramming epigenomes during stem cell derivation. Here we report on DNA methylation patterns in native monkey embryonic stem (ES) cells, fibroblasts and ES cells generated through somatic...
ORGANISM(S): Macaca mulatta 
2009-09-10 | E-GEOD-17981 | biostudies-arrayexpress
TranscriptomicsX-chromosome inactivation in monkey embryos and pluripotent stem cells
In this study, we explored x-inactivation in monkey embryos (ICM and TE separately) and pluripotent stem cells (IVF derived ES, SCNT-derived ES and monkey iPS) To elucidate x-inactivation in experimentally reprogrammed pluripotent cells, we derived pluripotent stem cells by both SCNT and iPS approac...
ORGANISM(S): Macaca mulatta 
2012-08-31 | E-GEOD-36252 | biostudies-arrayexpress
TranscriptomicsDiscovery of novel imprinted genes by transcriptional analysis of parthenogenetic embryonic stem cells
Parthenogenetic embryonic stem cells (PESCs) may have future utility in cell replacement therapies. We examined genome-wide mRNA expression profiles of monkey PESCs relative to ESCs derived from fertilized embryos. Several known paternally-imprinted genes were in the highly down-regulated group in P...
ORGANISM(S): Macaca mulatta 
2010-07-07 | E-GEOD-17964 | biostudies-arrayexpress
UnknownInduction of experimental cell division to generate cells with reduced chromosome ploidy.
Not available
S-EPMC12485136 | biostudies-literature
TranscriptomicsHuman embryonic stem cells derived by somatic cell nuclear transfer
In this study, we derived human embryonic stem cell via SCNT. Transcriptional analysis was performed to compare characteristics of SCNT-derived ESCs to their IVF counterpart. The transcriptomes of human embryonic stem cells (hESO-NT1) derived from human skin fibroblasts (HDF-f) via somatic cell nucl...
ORGANISM(S): Homo sapiens 
2013-05-15 | E-GEOD-46397 | biostudies-arrayexpress
UnknownLimitations of gene editing assessments in human preimplantation embryos.
Not available
S-EPMC9992379 | biostudies-literature
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