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MetabolomicsOxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers
Resistance to endocrine treatments and CDK4/6 inhibitors is considered a near-inevitability in most patients with estrogen receptor positive breast cancers (ER + BC). By genomic and metabolomics analyses of patients' tumours, metastasis-derived patient-derived xenografts (PDX) and isogenic cell line...
2023-06-27 | MTBLS3342 | MetaboLights
ProteomicsBlood-based Diagnostics of Pediatric Tuberculosis: A Prospective Case-controlled Study
Background Pediatric tuberculosis (TB) diagnosis is often challenging due to difficultly obtaining diagnostic respiratory specimens, which may contain low concentrations of Mycobacterium tuberculosis (Mtb) bacilli. However, we have reported that an immuno-affinity liquid chromatography-tandem mass s...
ORGANISM(S): Homo Sapiens 
2025-10-01 | PXD053274 | panorama
UnknownProtocol and Rationale for the International Lung Screening Trial.
Not available
S-EPMC7175983 | biostudies-literature
UnknownDrosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
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S-EPMC4426361 | biostudies-literature
UnknownGenetic studies of body mass index yield new insights for obesity biology.
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S-EPMC4382211 | biostudies-literature
UnknownNew genetic loci link adipose and insulin biology to body fat distribution.
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S-EPMC4338562 | biostudies-literature
UnknownRecurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections.
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S-EPMC3738837 | biostudies-literature
UnknownGlobal COVID-19 lockdown highlights humans as both threats and custodians of the environment.
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S-EPMC8135229 | biostudies-literature
UnknownGenome-wide association study of long COVID.
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S-EPMC12165857 | biostudies-literature
UnknownCommon variants associated with plasma triglycerides and risk for coronary artery disease.
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S-EPMC3904346 | biostudies-literature
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