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TranscriptomicsA High-Fat Diet and NAD+ Rescue Premature Aging in Cockayne Syndrome
Cockayne syndrome (CS) is an accelerated aging disorder characterized by progressive neurodegeneration caused by mutations in the genes encoding the DNA repair proteins CSA or CSB. Csbm/m mice were given a high-fat, caloric-restricted or resveratrol-supplemented diet. The high-fat diet rescued the p...
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-62194 | biostudies-arrayexpress
Metabolomics13C glucose labelling studies using 2D NMR is a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys
Background: The aim of this study is to determine the feasibility of using Nuclear Magnetic Resonance (NMR) tracer studies (13C-enriched glucose) to detect ex vivo de novo metabolism in the perfusion fluid and cortical tissue of porcine kidneys during hypothermic machine perfusion (HMP). Methods: Po...
2017-10-16 | MTBLS367 | MetaboLights
UnknownMitf-Mdel, a novel melanocyte/melanoma-specific isoform of microphthalmia-associated transcription factor-M, as a candidate biomarker for melanoma.
Not available
S-EPMC2839965 | biostudies-literature
UnknownPredicting performance in 4 x 200-m freestyle swimming relay events.
Not available
S-EPMC8282077 | biostudies-literature
ProteomicsCarbo-loading in fungal lung pathogens: a quantitative analysis of CAZyme abundance and resulting glycan populations
Herein we i) identify Coccidioides spp.-specific CAZymes by bioinformatically comparing the CAZyme repertoire (CAZome) of Coccidioides spp. to other common fungal lung pathogens and a non-pathogenic close fungal relative, ii) experimentally evaluate Coccidioides spp. CAZyme abundance in vivo and in...
ORGANISM(S): Homo sapiens (Human) 
2019-11-11 | PXD012459 | Pride
Cazymes Proteomics Glycomics Coccidioides Glycans Valley fever 
MetabolomicsMetabolite profile data of grapevine plants with brown wood streaking and grapevine leaf stripe (esca complex disease) symptoms

Leaf samples were obtained from Vitis vinifera ‘Malvasia Fina’ plants with well-characterized esca complex disease symptoms (n = 18) and from healthy uninfected plants (n = 6). Leaves from diseased plants were divided into three groups: asymptomatic (ASY), chlorotic (SY1), and scorched leaves (SY...

2021-11-21 | MTBLS353 | MetaboLights
UnknownAdvanced biofilm analysis in streams receiving organic deicer runoff.
Not available
S-EPMC6975536 | biostudies-literature
UnknownBRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group.
Not available
S-EPMC3413277 | biostudies-literature
TranscriptomicsGene expression signature reflects differentiation differences rather than telomere maintenance mechanism
A gene expression signature purporting to distinguish between telomerase and ALT immortalization has recently been described (Lafferty-Whyte et al., 2009). This was obtained as the intersection of two independent signatures, one obtained from cell lines and the other from a panel of liposarcomas, w...
ORGANISM(S): Homo sapiens 
2010-03-06 | E-GEOD-20559 | biostudies-arrayexpress
UnknownGait Speed as a Measure of Frailty and Outcomes After Lung Resection.
Not available
S-EPMC12857551 | biostudies-literature
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