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ProteomicsA Multi-Omic Analysis of Human Naive CD4 T cells
Technological advances in genomics, epigenomics, transcriptomics and proteomics have enabled massively parallel measurements across thousands of genes and gene products. Such high-throughput technologies have been extensively used to carry out genome-wide studies particularly in the context of disea...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-04-04 | MSV000079624 | MassIVE
ProteomicsA Multi-Omic Analysis of Human Naive CD4 T cells
Technological advances in genomics, epigenomics, transcriptomics and proteomics have enabled massively parallel measurements across thousands of genes and gene products. Such high-throughput technologies have been extensively used to carry out genome-wide studies particularly in the context of disea...
ORGANISM(S): Homo sapiens (Human) 
2015-11-12 | PXD000376 | Pride
Naive cd4+ t cells Memory cd4+ t cells Lc-msms 
TranscriptomicsComparison of bovine gd and ab T cell clones
Comparison of gd T cell clones with ab T cell clones that responded to the same antigen. Clones were identically stimulated with ConA/IL-2 and analyzed with two separate microarrays. Keywords: other
ORGANISM(S): Bos taurus 
2010-06-09 | E-GEOD-2704 | biostudies-arrayexpress
ProteomicsInheritance of old mitochondria controls early CD8+ T cell fate commitment and is regulated by autophagy - Pride 2
T cell immunity is impaired during ageing, particularly in memory responses needed for efficient vaccination. Autophagy and asymmetric cell division (ACD) are cell biological mechanisms key to memory formation, which undergo a decline upon ageing. However, despite the fundamental importance of these...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-21 | PXD053316 | Pride
Mitochondria Cd* t cells 
TranscriptomicsTranscriptome analysis of pancreatic progenitors differentiated from H9 human embryonic stem cells and induced pluripotent stem cells derived from a Mitchell-Riley Syndrome patient
Skin biopsies were obtained from a patient with Mitchell-Riley syndrome caused by a homozygous frame-shift mutation (c.1129C>T) in the RFX6 gene that leads to a premature stop codon (p.Arg377X). The patient suffered severe pancreatic agenesis, in common with other Mitchell-Riley syndrome patients. F...
ORGANISM(S): Homo sapiens 
2020-03-30 | E-MTAB-6626 | biostudies-arrayexpress
TranscriptomicsExpression data from Xenopus anterior gut RFX6 knockdown
Recently a new neonatal diabetes syndrome, Mitchell-Riley syndrome, was discovered. To identify the genetic cause of the syndrome homozygosity mapping was used, several chromosomal regions were linked to Mitchell-Riley syndrome. In situ hybridization of genes from one such region using model organ...
ORGANISM(S): Xenopus laevis 
2011-01-24 | E-GEOD-23642 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human 293 T cells infected with ASLV
Human 293T cells engineered to express the TVA receptor (see Mitchell et al., PLoS) infected with an ASLV vector. RNA isolated 48 hours later. ***PLEASE NOTE***; Series entries GSE1408 & GSE1409 no longer exist. All data discussed in the author's PLoS publication (PubMed ID 15314653) is available u...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1410 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of pancreatic endoderm differentiated from induced pluripotent stem cells derived from a patient with Mitchell-Riley Syndrome and her unaffected father
Skin biopsies were obtained from a patient with Mitchell-Riley syndrome and her unaffected father. The patient suffered neonatal diabetes, anaemia, intrauterine growth restriction, pancreatic hypoplasia and duodenal atresia, in common with other Mitchell-Riley syndrome patients. The disease was foun...
ORGANISM(S): Homo sapiens 
2020-10-23 | E-MTAB-9243 | biostudies-arrayexpress
ProteomicsLabel-free proteome analysis of small extracellular vesicles (sEV) expressing different HRS mutants.
Label-free proteome analysis of small extracellular vesicles (sEV) derived from WM9 cells expressing different HRS mutants: wild type (HRSWT), phospho-deficient (HRSS345A), and phospho-mimetic mutant HRS (HRSS345D).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-02-16 | MSV000088846 | MassIVE
GenomicsHomo sapiens strain:CD4+ T-Cells
HIV integration in latent and active human CD4-positive t-cells
PRJNA213846 | ENA
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