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ProteomicsThe biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder
We identified that peroxins were still expressed in Zellweger Spectrum Disorder (ZSD) and a subset of them accumulated on the mitochondrial membrane, which resulted in gross mitochondrial abnormalities and impaired mitochondrial metabolic function. In this complexome analysis we detected several per...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-06-25 | PXD024625 | Pride
Peroxisomes Mitocondrial quality control Mitochondria Peroxisomal biogenesis disorder Peroxisomal import Lc-msms Complexome profiling 
TranscriptomicsMitochondrial complex I-perturbed muscle remotely affects gene expression in the fat body in Drosophila
Purpose: Muscle injury caused by mitocondrial complex I disruption remotedly impairs mitochondrial activity and lipid homeostasis in the fat body . To gain insight into the corss talk between fat body and muscle, we performed a transcriptomic analysis in fat bodies of 3rd instar larvae with complex ...
ORGANISM(S): Drosophila melanogaster 
2017-06-20 | GSE100214 | GEO
GenomicsDrosophila melanogaster
Mitochondrial complex I-perturbed muscle remotely affects gene expression in the fat body in Drosophila
PRJNA390998 | ENA
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