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Small extracellular vesicles were purified from serum samples of patients with follicular thyroid carcinoma and follicular thyroid adenoma. Proteomic analysis was performed using these vesicles, and protein expression levels were compared between the two groups using label-free quantification.
ORGANISM(S): Homo Sapiens (human) 
Sialic acids are attached to glycoproteins via alpha2,3- or alpha2,6-linkages and play important roles in disease pathogenesis. Sialyl linkage-specific derivatization of intact N- and/or O-glycopeptides remains challenging because of the diverse reactive functional groups within peptides. In this re...
ORGANISM(S): Homo Sapiens (human) 
This study aimed to analyze ductal and squamous marker expression in pancreatic ductal adenocarcinoma (PDAC) cell lines under two-dimensional (2D) and three-dimensional (3D) culture conditions. Eight PDAC cell lines were examined using nanoLC-MS/MS-based proteomics.
ORGANISM(S): Homo Sapiens (human) 
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