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TranscriptomicsId2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease
Regulatory T (Treg) cells suppress the development of inflammatory disease, but our knowledge of transcriptional regulators that control this function remains incomplete. Here we show that expression of Id2 and Id3 in Treg cells was required to suppress development of fatal inflammatory disease. We ...
ORGANISM(S): Mus musculus 
2014-06-29 | E-GEOD-57682 | biostudies-arrayexpress
UnknownBystander-witnessed cardiopulmonary resuscitation by nonfamily is associated with neurologically favorable survival after out-of-hospital cardiac arrest in Miyazaki City District.
Not available
S-EPMC9586377 | biostudies-literature
GenomicsOpposing roles of E2A and Id3 that orchestrate and enforce the naive T cell fate
It is established that E2A and its antagonist, Id3, modulate developmental progression at the pre-TCR and TCR checkpoints. Here we show at a global scale how E2A promotes commitment to the T cell lineage and how pre-TCR mediated signalling affects E2A genome-wide occupancy. We find aberrant develo...
ORGANISM(S): Mus musculus 
2011-07-31 | E-GEOD-30518 | biostudies-arrayexpress
TranscriptomicsA genetic circuitry linking Id-proteins (Id2 and Id3) and the AKT-FOXO-mTORC1 axis to suppress innate-variant TFH cell development, maintain T cell quiescence and prevent lymphomagenesis.
It is now well established that the E- and Id-protein axis regulates multiple steps in lymphocyte development. However, it remains unknown as to how E- and Id-proteins mechanistically enforce and maintain the naïve T cell fate. Here we show that Id2 and Id3 suppressed the development and expansion o...
ORGANISM(S): Mus musculus 
2015-03-04 | E-GEOD-64779 | biostudies-arrayexpress
UnknownHuman T-cell leukemia virus type 1 may invalidate T-SPOT.TB assay results in rheumatoid arthritis patients: A retrospective case-control observational study.
Not available
S-EPMC7252607 | biostudies-literature
ModelsDong2014 - Mathematical modeling on helper t cells in a tumor immune system
This model gives a mathematical description of the interactions between tumor cells, cytotoxic T lymphocytes and helper T cells (HTCs) within the tumor microenvironment, with emphasis on the role played by HTCs. The effects and dynamics of adoptive cell immunotherapy and HTC recruitment are also spe...
2024-09-02 | BIOMD0000000783 | BioModels
Immuno-oncology 
UnknownXeniakonohana sp. nov. (Cnidaria, Octocorallia, Alcyonacea), a new soft coral species in the family Xeniidae from Miyazaki, Japan.
Not available
S-EPMC8831390 | biostudies-literature
UnknownPractical Application of Miyazaki Jitokko Chickens Selected for a Superior Allele at a Single Nucleotide Polymorphism Site in the Cholecystokinin Type A Receptor Gene.
Not available
S-EPMC7837808 | biostudies-literature
UnknownConcurrent Use of Teneligliptin and Canagliflozin Improves Glycemic Control with Beneficial Effects on Plasma Glucagon and Glucagon-Like Peptide-1: A Single-Arm Study.
Not available
S-EPMC6778556 | biostudies-literature
UnknownPhylogenetic analysis of env gene of bovine leukemia virus strains spread in Miyazaki prefecture, Japan.
Not available
S-EPMC5447981 | biostudies-literature
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