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TranscriptomicsRNA-seq of PSM tailbud tissues isolated from wild-type and cytoPFKFB3 mouse embryos cultured in different glucose concentration
To determine glycolytic flux-responsive genes in mouse presomitic mesoderm (PSM) cells, RNA sequencing (single-end) was performed using tailbud tissues isolated from wild-type and cytoPFKFB3 PSM explants cultured in different glucose conditions. Smart-seq2 protocol was used, and each condition inclu...
ORGANISM(S): Mus musculus 
2025-08-06 | E-MTAB-13694 | biostudies-arrayexpress
TranscriptomicsExpression data of human lung adenocarcinoma cell line H441 treated with TTF-1/NKX2-1 siRNA and TGF-beta
We determined and analyzed the effect of TTF-1/NKX2-1 on Smad3/Smad4 binding sites by ChIP-sequencing. We used expression microarrays to evaluate the effect of TTF-1/NKX2-1 siRNA on TGF-beta-induced gene expressions. H441 cells were transfected with siRNAs and treated with TGF-beta for RNA extractio...
ORGANISM(S): Homo sapiens 
2014-07-27 | E-GEOD-49675 | biostudies-arrayexpress
UnknownTranscytosis of murine-adapted bovine spongiform encephalopathy agents in an in vitro bovine M cell model.
Not available
S-EPMC2976421 | biostudies-literature
GenomicsSmad3, Smad4 and TTF-1/NKX2-1 binding sites in H441/A549 lung cancer cell lines
We evaluated the role of TTF-1/NKX2-1 on Smad3 and Smad4 binding in lung cancer cell lines. Smad3 binding sites in A549 cells and Smad3, Smad4, and TTF-1/NKX2-1 binding sites in H441 cells were determined by ChIP-seq.
ORGANISM(S): Homo sapiens 
2014-07-27 | E-GEOD-51509 | biostudies-arrayexpress
TranscriptomicsEffect of TTF-1/NKX2-1 expression on TGF-beta induced gene expression in A549 lung cancer cell line.
TTF-1/NKX2-1 was expressed by adenoviral vector and changes in gene expression were determined by RNA-sequencing. A549 cells were infected with Ad-TTF-1 or Ad-LacZ vectors and stimulated with TGF-beta for 24 hours or left untreated. Expression of polyA RNA was determined.
ORGANISM(S): Homo sapiens 
2014-07-27 | E-GEOD-56356 | biostudies-arrayexpress
UnknownRanking of binding and nonbinding peptides to MHC class I molecules using inverse folding approach: implications for vaccine design.
Not available
S-EPMC2639678 | biostudies-literature
UnknownAssociation of SLC6A3 variants with treatment-resistant schizophrenia: a genetic association study of dopamine-related genes in schizophrenia.
Not available
S-EPMC10929739 | biostudies-literature
TranscriptomicsRole of TTF-1/NKX2-1, Smad3 and Smad4 on lung cancer cell lines
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-07-27 | E-GEOD-51510 | biostudies-arrayexpress
UnknownPrediction of viral-host interactions of COVID-19 by computational methods.
Not available
S-EPMC9301933 | biostudies-literature
UnknownNEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
Not available
S-EPMC1134864 | biostudies-literature
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