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ProteomicsMKLP2 walks along microtubules and takes the CPC along for a ride
The mitotic kinesin-like Protein 2 (MKLP2, KIF20A) is essential for the proper execution of cytokinesis and required to ‘passage’ the chromosomal passenger complex (CPC) from the chromosomes in (pro)metaphase to the spindle midzone and equatorial cortex in anaphase. Together with MKLP1 (KIF23) and M...
ORGANISM(S): Homo sapiens (Human) 
2020-06-10 | PXD014665 | Pride
Mklp2 Motor proteins Chromosomal passenger complex 
UnknownMad2 inhibits the mitotic kinesin MKlp2.
Not available
S-EPMC3002031 | biostudies-literature
UnknownThe divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
Not available
S-EPMC5602324 | biostudies-literature
UnknownTargeting Aurora B to the equatorial cortex by MKlp2 is required for cytokinesis.
Not available
S-EPMC3672163 | biostudies-literature
UnknownMolecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
Not available
S-EPMC7337490 | biostudies-literature
GenomicsKIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development
KIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development
PRJNA427903 | ENA
UnknownKIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development.
Not available
S-EPMC6045631 | biostudies-literature
TranscriptomicsKIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development
Balanced symmetric and asymmetric divisions of neural progenitor cells (NPCs) are crucial for orderly progression of brain development, but the underlying mechanisms are not fully understood. Here, we report that mitotic kinesin KIF20A/MKLP2 interacts with RGS3 and plays a crucial role in controllin...
ORGANISM(S): Mus musculus 
2018-05-14 | GSE108624 | GEO
UnknownTwo mechanisms coordinate the recruitment of the chromosomal passenger complex to the plane of cell division.
Not available
S-EPMC5706991 | biostudies-literature
UnknownA bifurcated signaling cascade of NIMA-related kinases controls distinct kinesins in anaphase.
Not available
S-EPMC5551695 | biostudies-literature
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