Mm.1s - OmicsDI

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Unknown (145)
Genomics (136)
Proteomics (118)
Transcriptomics (84)
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Organisms

Allexis (113)
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Organisms

Homo sapiens (87)
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Repository

pride (113)
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geo (67)
biostudies-arrayexpress (56)
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Tissue

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Disease

Multiple myeloma (10)
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Technology Type

Mass Spectrometry (113)
Shotgun proteomics (59)
Affinity purification coupled with mass spectrometry proteomics (28)
Bottom-up proteomics (27)
Data-dependent acquisition (12)
Data-independent acquisition (4)
SWATH MS (4)
All-ion fragmentation (3)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
Top-down proteomics (2)
NMR spectroscopy (1)
Mass spectrometry assay (1)
Mass spectrometry (1)
Affinity proteomics (1)
Gel-based experiment (1)
HDMSE (1)
Immunopeptidomics (1)
SRM/MRM (1)

Instrument Platform

NextSeq 500 (5)
Orbitrap Fusion Lumos (4)
Illumina NovaSeq 6000 (3)
Illumina Genome Analyzer IIx (1)
NextSeq 2000 (1)
Illumina HiSeq 2500 (1)
Illumina HiSeq 2000 (1)
Flow injection analysis MS – POS (1)
Liquid Chromatography MS – NEG (1)
Liquid Chromatography MS – POS (1)
Nuclear Magnetic Resonance (NMR) - (1)

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2014 (15)
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2019 (11)
2015 (8)
2010 (8)
2012 (7)
2018 (7)
2016 (5)
2013 (5)
2011 (4)
2008 (4)
2009 (3)
2007 (2)

CHEBI ID

CHEBI:194970 (1)
CHEBI:53741 (1)
CHEBI:21555 (1)
CHEBI:76649 (1)
CHEBI:87694 (1)
CHEBI:87146 (1)
CHEBI:24579 (1)
CHEBI:55335 (1)
CHEBI:197827 (1)
CHEBI:84868 (1)
CHEBI:89996 (1)
CHEBI:89994 (1)
CHEBI:88706 (1)
CHEBI:89868 (1)
CHEBI:89854 (1)
CHEBI:89894 (1)
CHEBI:89852 (1)
CHEBI:89882 (1)
CHEBI:89883 (1)
CHEBI:89879 (1)
CHEBI:89880 (1)
CHEBI:86252 (1)
CHEBI:166785 (1)
CHEBI:169898 (1)
CHEBI:88430 (1)
CHEBI:88135 (1)
CHEBI:88587 (1)
CHEBI:88588 (1)
CHEBI:88576 (1)
CHEBI:88446 (1)

Metabolite Name

N-Acetyl-Glu (1)
N-Acetyl-Asp (1)
2,5-FurandicarboxylicÊacid (1)
N-Methyl-Asp (1)
2-oxoisocaproic acid (1)
N-Acetyl-Tyr (1)
N-Acetyl-Arg (1)
N-Acetyl-His (1)
N-Acetyl-Met (1)
(N6+N1)-Acetyl-Lys (1)
N1-Acetyl-Lys (1)
N-Acetyl-Ile (1)
N-Acetyl-Val (1)
N-Acetyl-Pro (1)
N-Acetyl-Ser (1)
N-Acetyl-Ala (1)
N-Acetyl-Gly (1)
HPHPA (1)
2-Hydroxy-3-methylvaleric acid (1)
3,4-Dihydroxybutyric acid (1)
N-Acetyl-Leu (1)
2-Hydroxyisovaleric acid (1)
P-Hydroxyhippuric acid (1)
3-Aminoisobutyric acid (1)
3-Hydroxyisobutyric acid (1)
3-Indoleacetic acid (1)
Oxalacetic acid (1)
2-hydroxyglutaric acid (1)
Guanidinopropionic acid (1)
Quinoline-4-carboxylic acid (1)

First Public Date

2022 (14)
2024 (12)
2021 (12)
2025 (10)
2014 (10)
2020 (6)
2017 (6)
2026 (5)
2019 (5)
2023 (3)
2016 (3)
2015 (3)
2018 (2)
2013 (2)

Modification

4'-dihydroxyphenylalanine (1)

Study type

Transcription profiling by array (32)
RNA-seq of coding RNA (7)
Comparative genomic hybridization by array (3)
ChIP-seq (3)
RNA-seq of coding RNA from single cells (2)
Unknown experiment type (1)
ChIP-chip by tiling array (1)
Genotyping by array (1)
Spatial transcriptomics by high-throughput sequencing (1)
Exome sequencing (1)
Ribo-seq (1)
Other (1)
Methylation profiling by array (1)
RNA-seq of total RNA (1)

Release Date

2022 (20)
2024 (19)
2014 (16)
2021 (16)
2025 (15)
2023 (14)
2020 (12)
2018 (12)
2012 (11)
2013 (9)
2010 (9)
2015 (8)
2017 (7)
2011 (7)
2019 (7)
2008 (5)
2016 (4)
2009 (3)
2007 (2)
2026 (2)
2006 (1)
2003 (1)
2002 (1)

Lab affiliation

University of Oxford (10)
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02215, USA (3)
Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany Frankfurt Cancer Institute, Frankfurt am Main, Germany Cardio-Pulmonary Institute, Frankfurt am Main, Germany (3)
The Institute of Cancer Research, London (3)
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (2)
Institute for Genetics, University of Cologne, 50674 Cologne, Germany (2)
Professor Laboratory Medicine and Pathology Mayo Clinic, Rochester, MN, USA (2)
Proteomics, Biomarker, Leibniz-Institut für analytische Wissenschaften -ISAS - e.V., Germany (2)
Proteomics, Leibniz-Institut für analytische Wissenschaften -ISAS - e.V., Germany (2)
University of Oxford University of Utrecht (2)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht (1)
CRUK Scotland Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (1)
Center for Neuroscience and Cell Biology (1)
Centre for Biologics Evaluation Biologics and Genetic Therapies Directorate Health Canada (1)
Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, University of Sydney, Camperdown, NSW, Australia (1)
Charles Perkins Centre, University of Sydney, Australia (1)
Charles University, Faculty of Science, Department of Parasitology, BIOCEV, Vestec 252 50, Czech Republic. (1)
Departament de Bioquímica i Biologia Molecular. Facultat de Veterinària. Universitat Autònoma de Barcelona. Cerdanyola del Vallès. 08193 Barcelona. Spain (1)
Department Cellular and Molecular Medicine KU Leuven Belgium (1)
Department of Anthropology, University of Oklahoma, USA (1)
Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642, USA (1)
Department of Cardiology, Tianjin Union Medical Center (1)
Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT, 84602 (1)
Department of Chemistry and Chemical Biology (1)
Department of Chemistry and Chemical Biology, Harvard University (1)
Department of Clinical Laboratory The Second Affiliated Hospital Guizhou University of Traditional Chinese Medicine (1)
Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, Michigan (1)
Department of Laboratory Medicine and Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, United States of America (1)
Department of Laboratory Medicine, Wiita Lab, University of California, San Francisco, USA (1)
Department of Microbiology at NYU Grossman School of Medicine. (1)

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Gene expression profiles of myeloma cells treated with NAE inhibitor

The transcriptional profile of the human multiple myeloma (MM) cell line MM.1S treated with MLN4924 vs control MM.1S cells was characterized by oligonucleotide microarray analysis, using the human U133 plus 2.0 Affymetrix GeneChip, according to previously described protocols for total RNA extraction...

ORGANISM(S): Homo sapiens

2012-05-01 | E-GEOD-33577 | biostudies-arrayexpress

Transcription profiling of human U266, MM.1s, KMS11, 8226/S multiple myeloma cell lines treated with arsenic

We used microarrays to examine changes in gene expression in multiple myeloma cell lines following treatment with arsenic trioxide and darinaparsin Experiment Overall Design: Four multiple myeloma cell lines (U266, MM.1s, KMS11, 8226/S) were treated with either arsenic trioxide (ATO) for 6, 24, or 4...

ORGANISM(S): Homo sapiens

2009-02-01 | E-GEOD-14519 | biostudies-arrayexpress

Global proteomics in MM.1S treated with pomalidomide or dipeptides

Global proteomics of Multiple Myeloma cell line MM.1S treated with pomalidomide or cyclic imide dipeptides for 10 h. The samples were labeled with TMT-16pro.

ORGANISM(S): Homo sapiens (Human)

2022-07-28 | PXD025336 | Pride

Transcriptomic signature induced in bone marrow Mesenchymal Stromal Cells (MSC) after interaction with malignant multiple myeloma cells: implications in myeloma progression.

Mesenchymal stromal cells (MSCs) derived from the BM of healthy donors (dMSCs) and myeloma patients (pMSCs) were co-cultured with the model myeloma cell line - MM.1S -, and the gene expression profile of MSCs induced by this interaction was analyzed using high density oligonucleotide microarrays. De...

ORGANISM(S): Homo sapiens

2014-11-23 | E-GEOD-46053 | biostudies-arrayexpress

Expression profile of MM.1S tumors folloiwing treatment with bortezomib

PRJNA509438 | ENA

Impact of Glucocorticoids and PI3K Inhibition on Gene Expression in Myeloma

We previously noted that combination glucocorticoids and PI3K inhibition induces synergistic cell death. To identify genes involved in myeloma cell death we examined mRNA expression in each individual treatment and in the combination. The glucocoriticoid resistant cells (MM.1RL) are used as a nega...

ORGANISM(S): Homo sapiens

2015-12-07 | E-GEOD-64704 | biostudies-arrayexpress

RNA sequencing of MM.1S and U266 cell lines after IT848 treatment

PRJNA824427 | ENA

RNA-seq analysis after JQKD82 treatment in human multiple myeloma cell line MM.1S

PRJNA622959 | ENA

Effect of EGCG to multiple myeloma MM.1S cells on gene expression

PRJNA1079665 | ENA

Transcription profiling of mouse multiple myeloma tumors and splenic B cells from transgenics overexpressing XBP-1s

Multiple myeloma (MM) evolves from highly prevalent premalignant condition termed Monoclonal Gammopathy of Undetermined Significance (MGUS). We report an MGUS-MM phenotype arising in transgenic mice with Emu-directed expression of the unfolded protein/ER stress response and plasma cell development ...

ORGANISM(S): Mus musculus

2007-11-06 | E-GEOD-6980 | biostudies-arrayexpress

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