Sort   by:  
 Page size 
TranscriptomicsExperimental analysis of oligonucleotide microarray design criteria to detect deletions by CGH
BACKGROUND: Microarray comparative genomic hybridization (CGH) is currently one of the most powerful techniques to measure DNA copy number in large genomes. In humans, microarray CGH is widely used to assess copy number variants in healthy individuals and copy number aberrations associated with var...
ORGANISM(S): Homo sapiens 
2008-07-26 | E-GEOD-12208 | biostudies-arrayexpress
TranscriptomicsCopy number variation in the genomes of twelve natural isolates of Caenorhabditis elegans
Background: Copy number variation is an important component of genetic variation in higher eukaryotes. The extent of natural copy number variation in C. elegans is unknown outside of 2 highly divergent wild isolates and the canonical N2 Bristol strain. Results: We have used array comparative genomic...
ORGANISM(S): Caenorhabditis elegans 
2010-05-17 | E-GEOD-19440 | biostudies-arrayexpress
TranscriptomicsRapid increase in frequency of gene copy-number variants during adaptive evolution in experimental Caenorhabditis elegans populations
Gene copy-number variation, which provides the raw material for the evolution of novel genes, is surprisingly widespread in natural populations. Experimental evolution studies have demonstrated an extremely high spontaneous rate of origin of gene duplications. When organisms are suboptimally adapte...
ORGANISM(S): Caenorhabditis elegans 
2015-04-15 | E-GEOD-67871 | biostudies-arrayexpress
Sort   by:  
 Page size