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TranscriptomicsMolecular basis for remission and tolerance induction in pediatric ITP
Children with newly diagnosed ITP that after 12 month enter remission, shows molecular separate entities. The molecular basis for remission and tolerance induction is characterized by gene transcriptional profiling Global gene expression profile in isolated T-cells from 6 children with newly diagnos...
ORGANISM(S): Homo sapiens 
2016-02-06 | E-GEOD-56232 | biostudies-arrayexpress
TranscriptomicsRemission in Polyarticular Juvenile Idiopathic Arthritis
Identify biomarkers to predict response to therapy in polyarticular juvenile idiopathic arthritis (JIA) using gene expression microarrays. 42 samples from 13 controls, 14 active patients, 9 patients in clinical remission with medication (CRM), and 6 patients in clinical remission without medication ...
ORGANISM(S): Homo sapiens 
2009-04-13 | E-GEOD-15645 | biostudies-arrayexpress
TranscriptomicsSNP arrays in matched diagnosis/remission samples of normal karyotype-acute myeloid leukemia
We analysed, by last-generation high-resolution SNP arrays, Normal Karyotype (NK)-AML patients at diagnosis (Dx) and remission (R) phases, in order to determine the number of tumor-associated copy number abnormalities (CNAs) and copy neutral-loss of heterozygosity (CN-LOH) regions per patient and to...
ORGANISM(S): Homo sapiens 
2010-12-31 | E-GEOD-21780 | biostudies-arrayexpress
ProteomicsPersistent epithelial barrier dysfunction and Periostin accumulation in histologic remission Eosinophilic Esophagitis
Patients with Eosinophilic esophagitis (EoE) require long-lasting resolution of inflammation to prevent fibrostenosis and dysphagia. However, the dissociation between symptoms and histologic improvement suggests persistent molecular drivers despite remission. We aimed to characterize persisting mole...
ORGANISM(S): Homo sapiens (Human) 
2024-09-23 | PXD052250 | Pride
Fibrosis Molecular remission Histologic remission Proteome Epithelial barrier dysfunction Eosinophilic esophagitis 
TranscriptomicsSingle cell RNA and CITE sequencing of cells from synovial tissue biopsies of healthy donors, and Rheumatoid Arthritis (RA) patients with active disease or sustained clinical remission
The dataset includes the raw FASTQ files generated from the 10x Genomics Single Cell 3’ v3.1 experiments. For samples processed with TotalSeq Hashtag reagents, the corresponding hashtag oligonucleotide and condition annotations are provided as separate .csv files. The processed matrices contain filt...
ORGANISM(S): Homo sapiens 
2024-12-06 | E-MTAB-14213 | biostudies-arrayexpress
TranscriptomicsEvaluation of transcriptomic profiles of peripheral blood myeloid cell subsets of RA patients in remission prior to cDMARD withdrawal, and at the point of flare / 6 months after in sustained remission
To test the contribution of distinct ST-DC populations to either autoimmunity and inflammation or sustained disease remission, we evaluated the phenotypes of their blood precursors in a human model of disease flare following treatment withdrawal in RA patients in disease remission (the BioRRA study,...
ORGANISM(S): Homo sapiens 
2024-12-09 | E-MTAB-14169 | biostudies-arrayexpress
TranscriptomicsMolecular basis for remission and tolerance induction in pediatric ITP
Children with newly diagnosed ITP that after 12 month enter remission, shows molecular separate entities. The molecular basis for remission and tolerance induction is characterized by gene transcriptional profiling
ORGANISM(S): Homo sapiens 
2016-02-06 | GSE56232 | GEO
TranscriptomicsGene expression profiles of pediatric IBD remission patients
Clinical remission is apparent when laboratory markers of inflammation are normal and clinical symptoms are absent. However, sub-clinical inflammation can still be present. A detailed analysis of the immune status during this inactive state of disease may provide a useful tool to subcategorize patie...
ORGANISM(S): Homo sapiens 
2013-10-04 | E-GEOD-33943 | biostudies-arrayexpress
ProteomicsSystems Signature Reveals Unique Remission-path of Diabetes Generated by Gastric Bypass Surgery
Gastric bypass surgery (GBP) emerging as a powerful tool for treatment of obesity has been applied for remission of diabetes. However, the GBP global molecular effects on diabetes remission independent of weight loss remain largely unknown. We profiled plasma metabolites and proteins of 10 normoglyc...
ORGANISM(S): Homo sapiens (Human) 
2017-12-13 | PXD008071 | Pride
Network Gastric bypass Diabetes Systems signature 
TranscriptomicsSmall nucleolar RNA and microRNA expression data from multiple sclerosis patients in relapse and remission.
Multiple sclerosis is a common inflammatory and degenerative disease that causes neurological disability. It affects young adults and its prevalence is higher in women. The most common form is manifested as a series of acute episodes of neurological disability (relapses) followed by a recovery phase...
ORGANISM(S): Homo sapiens 
2015-11-03 | E-GEOD-74579 | biostudies-arrayexpress
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