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TranscriptomicsEffect of amino acid availability on vitamin B12 production in Lactobacillus reuteri
Recent functional genomics and genome-scale modeling approaches indicated that B12 production in Lactobacillus reuteri could be improved by medium optimization. Here we show that a series of systematic single amino acid omissions could significantly modulate the production of B12 from nearly undetec...
ORGANISM(S): Lactobacillus reuteri F275 
2010-05-17 | E-GEOD-13391 | biostudies-arrayexpress
TranscriptomicsCGH analysis of 39 Lactococcus lactis strains.
Pangenome arrays contain DNA oligomers targeting several sequenced reference genomes from the same species. In microbiology these can be employed to investigate the often high genetic variability within a species by comparative genome hybridization (CGH). The biological interpretation of pangenome C...
ORGANISM(S): Lactococcus lactis subsp. cremoris 
2010-06-24 | E-GEOD-12638 | biostudies-arrayexpress
TranscriptomicsPeroxide stress in Sigma54 mutant and Wt
Analyses of the Wild type and the sigma 54 mutant strain NZ7306 with and without peroxide treatment: A Lactobacillus plantarum strain with a deletion in the alternative sigma factor 54 (?54) encoding gene rpoN, displayed a 100 fold higher sensitivity to peroxide as compared to its parental strain. T...
ORGANISM(S): Lactobacillus plantarum 
2008-05-08 | E-GEOD-11351 | biostudies-arrayexpress
TranscriptomicsClassifier analysis of gene expression profiles reveals a discriminatory gene set for soil containing different metals
Environmental pollution is a worldwide problem, and metals are the largest group of contaminants in soil. Microarray toxicogenomic studies with ecologically relevant organisms such as springtails, supplement traditional ecotoxicological research, but are presently rather descriptive. Classifier anal...
ORGANISM(S): Folsomia candida 
2010-02-04 | E-GEOD-19353 | biostudies-arrayexpress
ModelsTeusink2006 - Genome-scale metabolic network of Lactobacillus plantarum (iBT721)
Teusink2006 - Genome-scale metabolic network of Lactobacillus plantarum (iBT721) This model is described in the article: Analysis of growth of Lactobacillus plantarum WCFS1 on a complex medium using a genome-scale metabolic model. Teusink B, Wiersma A, Molenaar D, Francke C,...
2015-07-30 | MODEL1507180045 | BioModels
MetabolomicsMacrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques
Macrophages represent a major immune cell population in atherosclerotic plaques and play central role in the progression of this lipid-driven chronic inflammatory disease. Targeting immunometabolism is proposed as a strategy to revert aberrant macrophage activation to improve disease outcome. Here, ...
2021-03-05 | MTBLS2159 | MetaboLights
TranscriptomicsThe impact of glycerol on the metabolism of Lactobacillus reuteri
This SuperSeries is composed of the following subset Series: GSE11860: The impact of glycerol on the metabolism of Lactobacillus reuteri - Exploratory experiment GSE11861: The impact of glycerol on the metabolism of Lactobacillus reuteri - Main experiment Refer to individual Series
ORGANISM(S): Lactobacillus reuteri F275 
2010-05-20 | E-GEOD-11885 | biostudies-arrayexpress
TranscriptomicsImprovement of Lactobacillus plantarum Aerobic Growth by Comprehensive Transcriptome Analysis
An aerobic Lactobacillus plantarum culture displayed growth stagnation during early growth. Transcriptome analysis revealed that regain of growth after stagnation correlated with activation of CO2-producing pathways suggesting that limiting CO2-concentration induced stagnation. Analogously providing...
ORGANISM(S): Lactobacillus plantarum WCFS1 
2010-05-26 | E-GEOD-10194 | biostudies-arrayexpress
TranscriptomicsPocR regulates glycerol reduction, assembly of metabolosomes and vitamin B12 biosynthesis in Lactobacillus reuteri F275
Lactobacillus reuteri has been shown to encode a vitamin B12 biosynthesis pathway that is phylogenetically related to the one present in some representatives of gamma-proteobacteria such as Salmonella and Yersinia. Here we present evidence supporting that the similarities between these otherwise unr...
ORGANISM(S): Lactobacillus reuteri F275 
2010-05-17 | E-GEOD-13289 | biostudies-arrayexpress
TranscriptomicsListeria monocytogenes SOS response determined after mitomycin C exposure
The SOS response is a conserved pathway that is activated under certain stress conditions and is regulated by the repressor LexA and the activator RecA. The food-borne pathogen Listeria monocytogenes contains RecA and LexA homologs, but their roles in Listeria have not been established. In this stud...
ORGANISM(S): Listeria monocytogenes EGD-e 
2010-05-19 | E-GEOD-12634 | biostudies-arrayexpress
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