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TranscriptomicsEvaluation of microRNA expression in vehicle and metformin-treated breast cancer cells and evaluation of the dicer relevance
We have evaluated the microRNA expression profile of SUM159 cells stably infected with a control shRNA or a dicer-targeting shRNA treated with vehicle or metformin for 24 hrs at non cytotoxic doses. microRNA expression was evaluated from total RNA extracted from logaritmically growing SUM159 cells s...
ORGANISM(S): Homo sapiens 
2012-06-04 | E-GEOD-37038 | biostudies-arrayexpress
TranscriptomicsSexual polyploidization in Medicago sativa L.: impact on the phenotype, gene transcription and genome methylation
Polyploidization as the consequence of 2n gamete formation is a prominent mechanism in plant evolution. Studying its effects on the genome and its expression has both basic and applied interest. We crossed two diploid (2n=2x=16) M. sativa plants, a subsp. falcata seed parent and a coerulea x falcata...
ORGANISM(S): Medicago sativa 
2016-02-17 | E-GEOD-71559 | biostudies-arrayexpress
TranscriptomicsLamin A/C Is Required For ChAT-Dependent Neuroblastoma Differentiation: a microarray gene expression study
The mouse neuroblastoma N18TG2 clone is unable to differentiate and defective for the enzymes of the biosynthesis of neurotransmitters. The forced expression of choline acetyltransferase (ChAT) in these cells results in the synthesis and release of acetylcholine (Ach) and hence in the expression of ...
ORGANISM(S): Mus musculus 
2017-04-18 | E-GEOD-73591 | biostudies-arrayexpress
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