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TranscriptomicsCo-culture of human hematopoietic stem cells with osteoblasts affects mono/macrophage versus erythroid lineage choice.
Hematopoietic stem cells (HSCs) are located in the bone marrow in a specific microenvironment referred as the hematopoietic stem cell niche, where HSCs interact with a variety of stromal cells. Though several components of the stem cell niche have been identified, the regulatory mechanisms through w...
ORGANISM(S): Homo sapiens 
2013-05-10 | E-GEOD-38091 | biostudies-arrayexpress
TranscriptomicsEscherichia coli planktonic cultures: mono-species culture vs. mixed-species culture
Transcription profile of Escherichia coli cells in mono-species pure planktonic cultures was compared to that of E. coli cells in E. coli-Stenotrophomonas maltophilia dual-species planktonic cultures E. coli cells were separated from dual-species planktonic cultures before total RNA extraction to el...
ORGANISM(S): Escherichia coli K-12 
2013-12-30 | E-GEOD-24913 | biostudies-arrayexpress
TranscriptomicsA comparison of mono-culture and co-culture model containing fibroblasts
Organotypic three dimensional cultures of epithelial cells are grown at the air–liquid interface (ALI) and resemble the in vivo counterparts. Although the complexity of in vivo cellular responses could be better manifested in co-culture models in which additional cell-types such as fibroblasts were ...
ORGANISM(S): Homo sapiens 
2015-06-12 | E-MTAB-3462 | biostudies-arrayexpress
GenomicsBulk RNA sequencing of mono-culture and tri-culture microglia
Bulk RNA sequencing of mono-culture and tri-culture microglia
PRJNA1462388 | ENA
TranscriptomicsRNA-sequencing of Clostridioides difficile WT and luxS mutant both during mono-culture biofilms and co-culture biofilms with Bacteroides fragilis
5 conditions for RNA-sequencing: Mono-culture biofilms of C. difficile WT, C. difficile luxS mutant (insertional ClosTron mutant as described in DOI: 10.1128/JB.01980-12), B. fragilis (PRJEB29695), and co-cultures biofilms of C. difficile WT and luxS mutant with B. fragilis. These were used to compa...
ORGANISM(S): Bacteroides fragilis 
2018-12-16 | E-MTAB-7523 | biostudies-arrayexpress
GenomicsRNA-sequencing of Clostridioides difficile WT and luxS mutant both during mono-culture biofilms and co-culture biofilms with Bacteroides fragilis
RNA-sequencing of Clostridioides difficile WT and luxS mutant both during mono-culture biofilms and co-culture biofilms with Bacteroides fragilis
PRJEB30314 | ENA
GenomicsKetogulonigenium vulgare cells: co-culture mode vs. mono-culture mode
Ketogulonigenium vulgare cells: co-culture mode vs. mono-culture mode
PRJNA162307 | ENA
TranscriptomicsTranscriptome response of Salmonella enterica subsp. enterica serovar Typhimurium N-15 and Bifidobacterium thermophilum RBL67 in co-culture
Bifidobacterium thermophilum RBL67 (RBL67), a human fecal isolate and promising probiotic candidate, showed antagonistic and protective effects against Salmonella and Listeria in vitro. However, the underlying mechanisms fostering these health-related effects remain unknown. Therefor the transcripto...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2015-03-31 | E-GEOD-65716 | biostudies-arrayexpress
ProteomicsQuantitative profiling of the enzymatic activity of the protein lysine mono-methyltransferase SMYD2 using SILAC-based proteomics
The significance of non-histone lysine methylation in cell biology and human disease is an emerging area of research exploration, and small molecule inhibitors that selectively and potently target “writers” and “erasers” of methyl-lysine, such as the protein lysine mono-methyltransferase SMYD2, are ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080785 | MassIVE
TranscriptomicsBulk RNA sequencing of mono-culture and tri-culture microglia
Microglia are the immune cells of the central nervous system and are thought to be key players in both physiological and disease conditions. Several microglial features are poorly conserved between mice and human, such as the function of the neurodegeneration-associated immune receptor Trem2. Induce...
ORGANISM(S): Homo sapiens 
2026-06-29 | GSE330016 | GEO
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