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Accurate assignment of monoisotopic peaks is essential for the identification of peptides in bottom-up proteomics. Misassignment or inaccurate attribution of peptidic ions leads to lower sensitivity and fewer total peptide identifications. In the present work we present a performant, open-source, cr...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2020-11-17 | PXD019311 | Pride
Cross-linking/mass spectrometry has undergone a maturation process akin to standard proteomics by adapting key methods such as false discovery rate control and quantification. A seldom-used search setting in proteomics is the consideration of multiple (lighter) alternative values for the monoisotopi...
ORGANISM(S): Homo sapiens (Human) Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) 
2019-04-05 | PXD011121 | Pride
High-resolution MS/MS spectra of peptides can be deisotoped to identify monoisotopic masses of peptide fragments. The use of such masses should improve protein identification rates. However, deisotoping is not universally used and its benefits have not been fully explored. Here, we developed MS2-Dei...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-08-05 | PXD010587 | Pride
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