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MetabolomicsA thioredoxin-Serinc2-lipid signaling axis modulates mood-related behaviors in mice
Bipolar disorder (BD) shows strong heritability and distinct symptomatic subtypes. However, the molecular basis underlying subtype-specific features remains poorly understood. Here, we showed that Serinc2, a BD susceptibility gene encoding a L-serine transporter that regulates membrane lipid synthes...
2026-07-06 | MTBLS14954 | MetaboLights
TranscriptomicsTranscriptional profiling of monocytes of bipolar patients and controls
Bipolar disorder (BD) is a psychiatric disorder in which the core feature is pathological disturbance in mood ranging from extreme elation (mania) to severe depression. Study has shown an aberrant pro-inflammatory status of monocytes/macrophages in mood disorders. Therefore, this study aimed at stud...
ORGANISM(S): Homo sapiens 
2008-01-01 | E-MEXP-1275 | biostudies-arrayexpress
GenomicsThe Mood and Methylation Study (MMS)
The Mood and Methylation Study (MMS)
PRJNA821591 | ENA
GenomicsThe Mood and Methylation Study (MMS)
The Mood and Methylation Study (MMS)
PRJNA821589 | ENA
GenomicsHuman mood disorders risk gene synaptotagmin14 affects mania-like behaviors in mice
Human mood disorders risk gene synaptotagmin14 affects mania-like behaviors in mice
PRJNA1110201 | ENA
ProteomicsHunam gut microbiome metaproteomcis in LP1
The samples of gut micorbiota were collected in "Lunar Palace 365" experiment. The "Lunar Palace 365" experiment was a 370-day, multicrew, closed experiment carried out in a ground-based experimental BLSS platform named Lunar Palace 1. Deep metaproteomics data analysis was then performed for better ...
ORGANISM(S): human gut metagenome 
2023-05-10 | PXD027661 | Pride
Mood Lp1 Human gut microbiome 
UnknownNovel glutamatergic drugs for the treatment of mood disorders.
Not available
S-EPMC3747027 | biostudies-literature
GenomicsSerotonin receptor 4 in the hippocampus modulates mood and anxiety
Serotonin receptor 4 in the hippocampus modulates mood and anxiety
PRJNA662219 | ENA
TranscriptomicsIntellectual disability and mood disorder associated with partial deletion of the Neurexin 1 Gene
Abstract Background Neurexins are proteins located in the presynaptic membrane that bind postsynaptic ligands, neuroligins, neurexophilins, and dystrophoglycan. They exert profound effects on neurological function by mediating signalling across synapses and determining synaptic characteristics thro...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-23358 | biostudies-arrayexpress
GenomicsPromoter-wide profiling of DNA methylation in human neuroblastoma cells cultured with mood stabilizers.
Promoter-wide profiling of DNA methylation in human neuroblastoma cells cultured with mood stabilizers.
PRJNA564943 | ENA
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