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MetabolomicsCharacteristics of steroid hormones in systemic lupus erythematosus revealed by GC/MS-based metabolic profiling

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with a remarkable predominance in female, suggesting that steroid hormones may be involved in the pathogenesis. Herein, more than 70 kinds of steroids in urine were detected by gas chromatography/mass spectrometry (GC/MS) to reve...

2023-07-28 | MTBLS7766 | MetaboLights
MetabolomicsMetabolomic Responses of Guard Cells and Mesophyll Cells to Bicarbonate
Anthropogenic CO2 presently at 400 ppm is expected to reach 550 ppm in 2050, an increment expected to affect plant growth and productivity. Paired stomatal guard cells (GCs) are the gate-way for water, CO2, and pathogen, while mesophyll cells (MCs) represent the bulk cell-type of green leaves mainly...
2017-03-31 | MTBLS309 | MetaboLights
TranscriptomicsTranscription profiling of Arabidopsis seedlings exposed to ANep1 Treatment
In order to study the Nep1 responsive genes in Arabidopsis, experiments were performed with the Affymetrix GeneChip Arabidopsis ATH1 Genome Array (Santa Clara, CA; Cat # 900385). Experiment Overall Design: Seven-day old Arabidopsis seedlings were exposed to Nep1 (10 ug/mL) treatment or using steri...
ORGANISM(S): Arabidopsis thaliana 
2008-06-13 | E-GEOD-4638 | biostudies-arrayexpress
ProteomicsIdentification of novel blood biomarkers of treatment response in cystic fibrosis pulmonary exacerbations by label-free quantitative proteomics
Pulmonary exacerbations (PEx) are clinically impactful events for individuals with CF. Unfortunately, many CF individuals with PEx fail to regain their baseline lung function despite treatment. The objective of this study was to use unbiased proteomic technology (LC-MS/MS) to identify novel blood pr...
ORGANISM(S): Homo sapiens (Human) 
2020-05-27 | PXD016089 | Pride
Human Cystic fibrosis Plasma Blood Pulmonary exacerbations Lc-ms/ms 
ProteomicsProteome of the six eyes sand-spider Sicarius thomisoides venom
The six-eyed sand spider, Sicarius thomisoides, belongs to the Sicariidae family, whose venoms have recently been recognized for having a high toxic potential, similar to what has been demonstrated for the venom of spiders in the Loxosceles genus. However, with the exception of phospholipase D toxin...
ORGANISM(S): Sicarius thomisoides 
2025-11-10 | PXD062481 | Pride
Sicarius spider Venom proteome Lc-ms/ms 
TranscriptomicsGene expression data of postnatal Pitx2 deficient heart
Pitx2 is the homeobox gene located in proximity to the human 4q25 familial atrial fibrillation locus. Pitx2 haploinsufficient mice are prone to pacing induced atrial fibrillation indicating that reduced Pitx2 promotes an arrhythmogenic substrate within the atrium. Here, we inactivated Pitx2 in postn...
ORGANISM(S): Mus musculus 
2014-02-01 | E-GEOD-50399 | biostudies-arrayexpress
MetabolomicsMetabolomic Responses of Arabidopsis Suspension Cells to Bicarbonate under Light and Dark Conditions
Global CO2 level presently recorded at 400 ppm is expected to reach 550 ppm in 2050, an increment likely to impact plant growth and productivity. Using targeted LC-MS and GC-MS platforms we quantified 229 and 29 metabolites, respectively in a time-course study to reveal short-term responses to diffe...
2017-04-25 | MTBLS311 | MetaboLights
MetabolomicsRegulatory actors and alternative routes for Arabidopsis seed germination are revealed using a pathway‐based analysis of transcriptomic datasets
Regulation of seed germination by dormancy relies on a complex network of transcriptional and post‐transcriptional modifications during seed imbibition that controls seed adaptive responses to environmental cues. High‐throughput technologies have brought significant progress in the understanding of ...
2019-05-21 | MTBLS662 | MetaboLights
TranscriptomicsComparative gene expression profile of human limbal stromal cells, bone marrow mesenchymal cells, adipose cells and foreskin fibroblasts
Limbal stromal cells were reported to resemble mesenchymal stem cells (MSCs) with multipotential differentiation cability. However, little is known about their gene expression profiles compared to MSC derived from various sources. In this study, the gene expression profile of limbal stromal cells wa...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-38947 | biostudies-arrayexpress
TranscriptomicsTranscriptomics analyses of Gossypium hirsutum fiber in wild-type and immature fiber mutant
We performed a comparative genomics approach between im mutant and TM-1 in order to understand the function of im gene reducing the degree of fiber cell wall development. We compared transcriptome profiles of developing fibers (10, 17, and 28 days post anthesis (DPA)) between two NILs using Affymetr...
ORGANISM(S): Gossypium hirsutum 
2014-05-01 | E-MEXP-3901 | biostudies-arrayexpress
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