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Signaling pathways that converge on two different transcription factor complexes, NFκB and AP-1, have been identified in estrogen receptor (ER)-positive breast cancers resistant to the antiestrogen, tamoxifen. In this study, biomarkers co-ordinately up-regulated by NFKB and AP-1 with prognositic si...
ORGANISM(S): Homo sapiens 
Total RNA was extracted from FFPE samples of 139 chemotherapy-naïve hormone-receptor-negative breast cancers pooled from three sample sources and assayed for the expression of 21 genes within two previously reported microarray-derived prognostic signatures in 6 RT-PCR multiplexes. RT-PCR gene expre...
ORGANISM(S): Homo sapiens 
Assessment of transcriptome stability in Paxgene collected whole blood and representation of hematopoietic lineages of whole blood transcriptome using single primer isothermal amplification probes without globin reduction protocols. As well as the stability assessment of Paxgene collected samples we...
ORGANISM(S): Homo sapiens 
Gene expression changes caused by estrogen treatment of breast cancer cells that re-express ERalpha was investigated by infecting ER-negative MDA-MB-231 breast cancer cells for 24 h with recombinant adenovirus encoding full-length human ERalpha (Ad-ERalpha) or control vector (Ad-LacZ), and treating ...
ORGANISM(S): Homo sapiens 
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