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TranscriptomicsTranscription profiling of aortic media from L-NAME and atorvastatin treated male rats
One-month-old male Fischer 344 rats with an initial body weight of 150 g were used for this study and were divided into 7 groups: a control group (30 days), 2 groups intoxicated with L-NAME (50 mg/kg per day in the drinking water; Sigma Chemical Co) for 15 and 30 days, 2 groups treated with atorvast...
ORGANISM(S): Rattus norvegicus 
2006-12-31 | E-MEXP-33 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila infected with the parasitoid wasps Leptopilina boulardi and L. heterotoma to investigate infection strategies
Although host-parasitoid interactions are becoming well characterized at the organismal and cellular levels, much remains to be understood of the molecular bases for the host immune response and the parasitoids’ ability to defeat this immune response. Leptopilina boulardi and L. heterotoma, two c...
ORGANISM(S): Drosophila melanogaster 
2008-03-13 | E-GEOD-8938 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of zebrafish livers following exposure to 17 alpha-ethynylestradiol (EE2) at 0, 15, 40, or 100 ng/L
Genomic, proteomic, and metabolomic technologies continue to receive increasing interest from environmental toxicologists. This interest is due to the great potential of these technologies to identify detailed modes of action and to provide assistance in the evaluation of a contaminant?s risk to aq...
ORGANISM(S): Danio rerio 
2007-02-24 | E-TABM-105 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human colon carcinoma cells Caco-2 response to N-acetyl-L-cystein (10 mM) (1,12 and 24 hour time-series)
Caco-2 human colon carcinoma cells were seeded at a density of 9 x 10 000 cells/cm2 and the cell cultures were grown for 24 hours before addition of 10 mM N-Acetyl-L-Cystein. RNA obtained from cultures grown for 1, 12 and 24 hrs after NAC treatment were compared to RNA from untreated cells at the c...
ORGANISM(S): Homo sapiens 
2005-07-15 | E-MEXP-147 | biostudies-arrayexpress
TranscriptomicsCandida albicans DOPA-grown cells
The fungal pathogen Candida albicans produces dark-pigmented melanin when grown in a basal medium containing 1 mM l-DOPA as melanin substrate. In the widely used C. albicans strain SC5314, melanin appeared after 3-4 days of incubation in l-DOPA medium. The experiment was designed to reveal cadidat...
ORGANISM(S): Candida albicans 
2010-07-07 | E-GEOD-20338 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human NHEK cells response to 2mM N-Acetyl-L-cystein (NAC) treatment - 1,12, 24 hour time-series
NHEK cells were plated at a density of 8 x 10 000/cm2 and the cell cultures were grown for 24 hours before addition of 2 mM N-Acetyl-L-Cystein. RNA obtained from cultures grown for 1, 12 and 24 hrs after NAC treatment were compared to RNA from untreated cells at the corresponding time points. I.e 1...
ORGANISM(S): Homo sapiens 
2005-07-15 | E-MEXP-146 | biostudies-arrayexpress
UnknownMORA and EnsembleTFpredictor: An ensemble approach to reveal functional transcription factor regulatory networks.
Not available
S-EPMC10688744 | biostudies-literature
TranscriptomicsTranscription profiling of mouse macrophages infected with Leishmania major or Leishmania donovani
Murine bone marrow derived macrophages were infected with Leishmania major or Leishmania donovania promastigotes, allowed to phagocytose latex beads or not treated. Gene expression profiles were compared to identify i) the effect of Leishmania infection; ii) the differences in effects between L. maj...
ORGANISM(S): Mus musculus 
2008-02-05 | E-MEXP-1254 | biostudies-arrayexpress
UnknownMorA defines a new class of regulators affecting flagellar development and biofilm formation in diverse Pseudomonas species.
Not available
S-EPMC523210 | biostudies-literature
TranscriptomicsDifferential Targeting of the E-Cadherin and b-Catenin Complex by Gram-positive Probiotic Lactobacilli Improves Epithelial Barrier Function
The intestinal ecosystem is balanced by dynamic interactions between resident and incoming microbes, the gastrointestinal barrier, and the mucosal immune system. However, in the context of inflammatory bowel diseases (IBD) where the integrity of the gastrointestinal barrier is compromised, resident ...
ORGANISM(S): Homo sapiens 
2012-02-10 | E-MEXP-3445 | biostudies-arrayexpress
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