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Collagen tracks deposited by breast cancer cells contain specific miRNAs which reprogram non-invasive cells into highly pro-metastatic ones by inducing a partial epithelial–mesenchymal transition (EMT) associated with an increase in ECM degradation and cell invasiveness.
ORGANISM(S): Homo sapiens 
Mycobacterium tuberculosis, the main causative agent of human tuberculosis, is transmitted from person to person via small droplets containing very few bacteria. Optimizing the chance to seed in the lung is therefore a major adaptation to favor survival and dissemination in the human population. He...
ORGANISM(S): Mycobacterium tuberculosis H37Rv_2009 
2022-02-16 | PXD024319 | Pride
By genome comparison of 30 MTBC strains, we identified three SNPs affecting the phoPR genes of members of the animal and M. africanum lineages that were not seen in the M. tuberculosis sensu-stricto genomes. The genes phoPR encode a two component regulatory system that is known for its strong impact...
ORGANISM(S): Mycobacterium tuberculosis 
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