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TranscriptomicsPrognostic significance of copy-number alterations in multiple myeloma
Purpose Chromosomal aberrations are a hallmark of multiple myeloma but their global prognostic impact is largely unknown. Methods We performed a genome-wide analysis of malignant plasma cells from 192 newly myeloma patients using high-density, single-nucleotide polymorphism (SNP) arrays to identify...
ORGANISM(S): Homo sapiens 
2009-08-19 | E-GEOD-12896 | biostudies-arrayexpress
UnknownLenalidomide Maintenance After Autologous Stem-Cell Transplantation in Newly Diagnosed Multiple Myeloma: A Meta-Analysis.
Not available
S-EPMC5652871 | biostudies-literature
TranscriptomicsGene expression profile alone is inadequate in predicting complete response in multiple myeloma
We have analyzed gene expression microarray datasets from four different clinical trials to assess accuracy of gene expression based signature in predicting treatment complete response in patients with multiple myeloma. Two of four datasets were made available via The Intergroupe Francophone du Myél...
ORGANISM(S): Homo sapiens 
2014-04-21 | E-GEOD-55145 | biostudies-arrayexpress
UnknownProspective Evaluation of Magnetic Resonance Imaging and [18F]Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography at Diagnosis and Before Maintenance Therapy in Symptomatic Patients With Multiple Myeloma Included in the IFM/DFCI 2009 Trial: Results of the IMAJEM Study.
Not available
S-EPMC5578392 | biostudies-literature
UnknownHealth-Related Quality-of-Life Results From the Open-Label, Randomized, Phase III ASPIRE Trial Evaluating Carfilzomib, Lenalidomide, and Dexamethasone Versus Lenalidomide and Dexamethasone in Patients With Relapsed Multiple Myeloma.
Not available
S-EPMC5791840 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis to assess spiking
Transcript profiling is crucial to study biological systems and various platforms have been implemented to survey mRNAs at the genome scale. We have assessed the characteristics of the CATMA microarray designed for Arabidopsis thaliana transcriptome analysis, and compared it with two commercial plat...
ORGANISM(S): Arabidopsis thaliana 
2004-11-23 | E-MEXP-197 | biostudies-arrayexpress
TranscriptomicsGenetic adaptability of cancer cells under treatment selection pressure in multiple myeloma patients.
Purpose Despite advances and significant improvement in survival, multiple myeloma (MM) remains incurable and nearly all patients relapse after treatment. Previous studies have shown a complex spectrum of diverse genetic alterations in almost all patients, but evolution of genomic rearrangements th...
ORGANISM(S): Homo sapiens 
2013-02-13 | E-GEOD-25262 | biostudies-arrayexpress
TranscriptomicsExpression of genetic adaptability of cancer cells under treatment selection pressure in multiple myeloma patients
Series GSE25262 patients on expression side. [Exon study] 11 myeloma patients at diagnosis and relapse examined with Exon expression chip
ORGANISM(S): Homo sapiens 
2013-02-13 | E-GEOD-37414 | biostudies-arrayexpress
TranscriptomicsMinor clone provides a reservoir for relapse in multiple myeloma
In this study we addressed subclonal evolutionary process after treatment and subsequent relapse in multiple myeloma (MM) in a cohort of 24 MM patients treated either with conventional chemotherapy or with the proteasome inhibitor, bortezomib. Because MM is a highly heterogeneous disease coupled wit...
ORGANISM(S): Homo sapiens 
2013-02-13 | E-GEOD-37469 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis mutants (elo2, elo3, drl1-2 and ang4) vs the wild type Ler strain
Microarray transcript profiling and RNA interference are two new technologies crucial for large-scale gene function studies in multicellular eukaryotes. Both rely on sequence-specific hybridization between complementary nucleic acid strands, inciting us to create a collection of gene-specific sequen...
ORGANISM(S): Arabidopsis thaliana 
2004-05-07 | E-MEXP-30 | biostudies-arrayexpress
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