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ProteomicsIdentification of ELC interacting proteins in zebrafish heart
The essential myosin light chain (ELC) is part of the cardiac myosin motor regulating the contractility of the heart. Recently, we have demonstrated ELC phosphorylation to be responsible not only for basal maintenance of cardiac contractility, but also for the adaptation of sarcomere function to inc...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2022-07-24 | PXD016357 | Pride
Myosin light chain Elc Co-immunoprecipitation Phosphorylation 
ProteomicsAnalysis of myosin light chain migration pattern in 2D gels of human left ventricular proteins
The myosin light chain protein family consists of two classes, the regulatory myosin light chains (RLC) and the essential myosin light chains (ELC). Functionally, the MLC proteins are directly involved in sarcomeric activity and force transmission contributing to cardiac contractility. Besides regul...
ORGANISM(S): Homo sapiens (Human) 
2022-07-24 | PXD033908 | Pride
Cardiomyocytes Essential myosin light chains (elc) Phosphorylation Regulatory myosin light chains (rlc) 
ProteomicsAnalysis of myosin light chain migration pattern in 2D gels of human left ventricular proteins - proximity labeling
NIMA-related kinase 9 (NEK9) was identified to interact with the essential myosin light chain (ELC). To validate these findings ascorbate peroxidase (APEX) catalyzed proximity labeling (Hung et al. Nat Protoc. 2016) was performed. To do so, human ELC fused to APEX was overexpressed in HEK293 cells. ...
ORGANISM(S): Homo sapiens (Human) 
2022-07-24 | PXD034115 | Pride
Bioid Nek9 Elc 
UnknownPrevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.
Not available
S-EPMC7880913 | biostudies-literature
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