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TranscriptomicsMicroarray Expression Data from Haematopoietic Differentiated Human Embryonic Stem Cells
The underlying mechanisms which are responsible and govern early haematopoietic differentiation during development are poorly understood. Gene expression comparison between pluripotent human embryonic stem cells and earliest haematopoietic progenitors may reveal novel transcripts and pathways and p...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29115 | biostudies-arrayexpress
ProteomicsMice bone marrow-derived dendritic cells (BMDC) infected by Listeria: extracellular vesicles (EVs) proteome and PTMs
In this study, we aimed to determine the role of EVs derived from Lm-infected DCs in the innate response, and the potential role of HDAC6 in DEV loading under these conditions. Our results show that Lm infection induced an elevated production of DEVs. Lm infection also altered protein sorting. Inter...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-30 | PXD033998 | Pride
Multiplexed quantitative proteomics Ubiquitinilation Acetylation Extracellular vesicles from dendritic cells Hdac6-ko 
ProteomicsMice bone marrow-derived dendritic cells (BMDC) infected by Listeria: cell lysate proteome and PTMs
In this study, we aimed to determine the role of EVs derived from Lm-infected DCs in the innate response, and the potential role of HDAC6 in DEV loading under these conditions. Ourresults show that Lm infection induced an elevated production of DEVs. Lm infection also altered protein sorting. Intere...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-30 | PXD033995 | Pride
Multiplexed quantitative proteomics Ubiquitinilation Mouse Acetylation Hdac6-ko Bmdendritic cells 
TranscriptomicsA human ESC model for MLL-AF4 reveals an impaired early human hemato-endothelial specification
The MLL-AF4 fusion gene is a hallmark genomic aberration in high-risk acute lymphoblastic leukemia in infants. Although it is well-established that MLL-AF4 arises pre-natally during human development, its effects on hematopoietic development in utero remains unexplored. We have created a human-spec...
ORGANISM(S): Homo sapiens 
2011-06-09 | E-GEOD-29869 | biostudies-arrayexpress
UnknownPredictive factors of six-week mortality in critically ill patients with SARS-CoV-2: A multicenter prospective study.
Not available
S-EPMC9020190 | biostudies-literature
UnknownSpatiotemporal Characteristics of the Largest HIV-1 CRF02_AG Outbreak in Spain: Evidence for Onward Transmissions.
Not available
S-EPMC6421502 | biostudies-literature
UnknownThe utility of Next Generation Sequencing for molecular diagnostics in Rett syndrome.
Not available
S-EPMC5613000 | biostudies-literature
UnknownCharacteristics and predictors of death among 4035 consecutively hospitalized patients with COVID-19 in Spain.
Not available
S-EPMC7399713 | biostudies-literature
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