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GenomicHepatitis C Antiviral Long-term Treatment Against Cirrhosis (HALT-C)

Reprinted from http://www.haltctrial.org/

Purpose

The Hepatitis C Antiviral Long-term Treatment against Cirrhosis (HALT-C) Trial is a randomized controlled trial designed to evaluate the safety and efficacy of long-term use of pegylated inte...

phs000430 | dbGaP
MetabolomicsImpact of acute lymphoblastic leukemia induction therapy: findings from metabolomics on non-fasted plasma samples from a biorepository

INTRODUCTION: Acute lymphoblastic leukemia (ALL) is among the most common cancers in children. With improvements in combination chemotherapy regimens, the overall survival has increased to over 90%. However, the current challenge is to mitigate adverse events resulting from the c...

2021-08-12 | MTBLS2394 | MetaboLights
TranscriptomicsA novel post-translational mechanism controlling the oncogenic activity of c-Myc is enhanced in poor outcome breast cancer
Examination of Pin1-regulated Myc target genes in a human breast epithelial cell line. Two samples: control GFP-expressing MCF10A-Myc cells and Pin1-expressing MCF10A-Myc cells.
ORGANISM(S): Homo sapiens 
2014-05-28 | E-GEOD-33776 | biostudies-arrayexpress
UnknownRegulation of Ca2+/calmodulin kinase II by a small C-terminal domain phosphatase.
Not available
S-EPMC2724867 | biostudies-literature
TranscriptomicsWhole Genome Sequencing Informs Therapeutic Selection for Pancreatic Cancer
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden. We performed whole genome sequencing and CNV analysis of 100 pancreatic ductal adenocarcinomas. Chromosomal rearrangements leading to gene disruption were frequent, affecting genes known to be important in pa...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-61502 | biostudies-arrayexpress
UnknownExpression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells.
Not available
S-EPMC4516428 | biostudies-literature
UnknownPolyanions provide selective control of APC/C interactions with the activator subunit.
Not available
S-EPMC6925294 | biostudies-literature
ProteomicsPhosphate-binding pocket on cyclin B governs CDK substrate phosphorylation and mitotic timing
Cell cycle progression is governed by complexes of the cyclin-dependent kinases (CDKs) and their regulatory subunits cyclin and Cks1. CDKs phosphorylate hundreds of substrates, often at multiple sites. Multisite phosphorylation depends on Cks1, which binds initial priming phosphorylation sites to pr...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2025-05-19 | PXD062428 | Pride
Human Lfq Cdk Phosphoproteomics Yeast Lcms 
MetabolomicsEnvironmental Chemical Diethylhexyl Phthalate Alters Intestinal Microbiota Community Structure and Metabolite Profile in Mice
Exposure to environmental chemicals during windows of development is a potentially contributing factor in gut microbiota dysbiosis, and linked to chronic diseases and developmental disorders. We used a community-level model of microbiota metabolism to investigate the effects of diethylhexyl phthalat...
2022-01-17 | MTBLS861 | MetaboLights
UnknownQuantitative liver function tests improve the prediction of clinical outcomes in chronic hepatitis C: results from the Hepatitis C Antiviral Long-term Treatment Against Cirrhosis Trial.
Not available
S-EPMC3298578 | biostudies-literature
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