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TranscriptomicsGene expression profiles in 132 laser microdissected colorectal cancer tissues
Tissues from another series of 132 patients with colorectal cancer were collected by laser micro-dissection with the Leica Laser Microdissection System (Leica Microsystems). Gene expression levels obtained from 132 microdissected colorectal tumors were compared with microdissected normal colon epith...
ORGANISM(S): Homo sapiens 
2011-08-31 | E-GEOD-21815 | biostudies-arrayexpress
TranscriptomicsRec8 guides canonical Spo11 distribution along yeast meiotic chromosomes
Spo11-mediated DNA double strand breaks (DSBs) that initiate meiotic recombination are temporally and spatially controlled. The meiotic cohesin Rec8 has been implicated in regulating DSB formation, but little is known about the features of their interplay. To shed light on this point, we investigate...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-18 | E-GEOD-8422 | biostudies-arrayexpress
TranscriptomicsDistribution of different proteins related to sister chromatid cohesion during the cell cycle.
This series is a supplementary data set for the manuscript titled "Cohesin relocation from sites of chromosomal loading to places of convergent transcription" All data shown in the paper were registered (30 ChIP-chip and one transcription data). Experimental design: 1. Type of experiment: a. ChIP ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-09 | E-GEOD-1461 | biostudies-arrayexpress
TranscriptomicsProtein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I
Segregation of homologous maternal and paternal centromeres to opposite poles during meiosis I depends on post-replicative crossing over between homologous non-sister chromatids, which creates chiasmata and therefore bivalent chromosomes. Destruction of sister chromatid cohesion along chromosome arm...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-11 | E-GEOD-4791 | biostudies-arrayexpress
TranscriptomicsGene expression profiles in 74 laser microdissected colorectal cancer tissues
Tissues from another series of 74 patients with colorectal cancer were collected by laser micro-dissection with the Leica Laser Microdissection System (Leica Microsystems). Gene expression levels obtained from 74 microdissected colorectal tumors were compared with 5 microdissected normal colon epith...
ORGANISM(S): Homo sapiens 
2013-08-31 | E-GEOD-35279 | biostudies-arrayexpress
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