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GenomicsRAR/RXR binding dynamics distinguishes pluripotency from differentiation-associated cis-regulatory elements
In mouse embryonic cells, a retinoic acid (RA) stimulation triggers a massive change of gene expression leading the pluripotent, proliferating cells to a lineage-specific differentiation process. The retinoic acid receptor (RAR) plays a key role in this response by inhibiting pluripotency-maintainin...
ORGANISM(S): Mus musculus 
2015-04-17 | E-GEOD-56893 | biostudies-arrayexpress
GenomicsWhole genome sequencing - samples
Mutational landscapes of primary triple negative breast cancers - WGS
EGAD00001000115 | EGA
GenomicsRNA seq - samples
Mutational landscapes of primary triple negative breast cancers - RNA seq
EGAD00001000132 | EGA
GenomicsEGAD00010000148
tumour samples using Affymetrix Genome-Wide SNP6.0 arrays
EGAD00010000148 | EGA
GenomicsExome sequencing - samples
Mutational landscapes of primary triple negative breast cancers - Exomes
EGAD00001000113 | EGA
GenomicsThe clonal and mutational evolution spectrum of primary triple negative breast cancers
Primary triple negative breast cancers (TNBC) represent approximately 16% of all breast cancers and are a tumour type defined by exclusion,for which comprehensive landscapes of somatic mutation have not been determined. Here we show in 104 early TNBC cases, that at the time of diagnosis these cancer...
EGAS00001000132 | EGA
UnknownIncreased diagnostic and new genes identification outcome using research reanalysis of singleton exome sequencing.
Not available
S-EPMC6777617 | biostudies-literature
UnknownImmunocompromised patients with acute respiratory distress syndrome: secondary analysis of the LUNG SAFE database.
Not available
S-EPMC5998562 | biostudies-literature
UnknownIdentifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database.
Not available
S-EPMC6203969 | biostudies-literature
UnknownSPEN haploinsufficiency causes a neurodevelopmental disorder overlapping proximal 1p36 deletion syndrome with an episignature of X chromosomes in females.
Not available
S-EPMC8008487 | biostudies-literature
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