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Kidneys are enlarged by aberrant proliferation of tubule epithelial cells leading to the formation of numerous cysts, nephron loss, and interstitial fibrosis in polycystic kidney disease (PKD). Pioglitazone (PIO), a PPAR-M-NM-3 agonist, decreased cell proliferation, interstitial fibrosis and inflamm...
ORGANISM(S): Rattus norvegicus 
Small extracellular vesicles were purified from serum samples of patients with follicular thyroid carcinoma and follicular thyroid adenoma. Proteomic analysis was performed using these vesicles, and protein expression levels were compared between the two groups using label-free quantification.
ORGANISM(S): Homo Sapiens (human) 
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