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ProteomicsPersonalised phosphoproteomics extracts functional signalling
Protein phosphorylation dynamically integrates environmental and cellular information to control virtually all biological processes. Identifying functional phosphorylation amongst the thousands of phosphosites regulated by a perturbation at a global scale is a major challenge. Here, we introduce pe...
ORGANISM(S): Homo sapiens (Human) 
2021-12-06 | PXD027198 | Pride
Phosphoproteomics Human Exercise Skeletal muscle Insulin 
TranscriptomicsOncogenic Nras has a bimodal effect on hematopoietic stem cells promoting proliferation and self-renewal
Pre-leukemic mutations are thought to promote clonal expansion of hematopoietic stem cells (HSCs) by increasing self-renewal and competitiveness. However, mutations that increase HSC proliferation tend to reduce competitiveness and self-renewal potential, raising the question of how a mutant HSC can...
ORGANISM(S): Mus musculus 
2014-03-14 | E-GEOD-45194 | biostudies-arrayexpress
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