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Genome-wide expression profiling was used to identify genes that showed altered expression in response to treatment with the saponins tomatidine, tomatine and the sterol biosynthesis inhibitory compound fenpropimorph; Growth inhibition by the compounds was monitored by measuring the OD600nm. Cells w...
ORGANISM(S): Saccharomyces cerevisiae 
Complete set of bam files associated with study EGAS00001000622
Mantle cell lymphoma (MCL) is an aggressive malignancy characterized by poor prognosis, underscoring the need for novel therapeutic strategies1. In this study, we employed large-scale pharmacological profiling of 16 pathway inhibitors across more than 100 hematological cell line models to identify n...
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