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ProteomicsProteomic analysis of renal biomarkers of kidney allograft fibrosis – a study in renal transplant patients
Renal transplantation is the preferred treatment of end stage renal disease, but allograft survival is limited by development of interstitial fibrosis and tubular atrophy in response to various stimuli. Much effort has been put into identifying new protein markers of fibrosis to support the diagnosi...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD017867 | Pride
Nano-lc-msms Transplant Kidney fibrosis 
TranscriptomicsThe regenerative response in the pig liver remnant varies with the degree of resection and rise in portal pressure.
Following parenchymal loss, the liver regenerates restoring normal mass and metabolic function. Prevailing theories on triggering events leading to regeneration include humoral, metabolic and flow-mediated mechanisms, the latter emphasizing the importance of shear stress mediated nitric oxide (NO) r...
ORGANISM(S): Sus scrofa 
2008-01-14 | E-GEOD-6860 | biostudies-arrayexpress
UnknownThe effect of spironolactone on calcineurin inhibitor induced nephrotoxicity: a multicenter randomized, double-blind, clinical trial (the SPIREN trial).
Not available
S-EPMC5934785 | biostudies-literature
TranscriptomicsChanges in cholesterol homeostasis and acute phase response following pulmonary exposure to multi-walled carbon nanotubes links carbon nanotube exposure to risk of cardiovascular disease
Adverse lung effects in rodents following pulmonary exposure to multi-walled carbon nanotubes (MWCNT) are well documented. However, systemic effects are less understood. Prospective epidemiological studies have shown increased cardiovascular disease risk after pulmonary exposure to airborne particle...
ORGANISM(S): Mus musculus 
2015-02-02 | E-GEOD-61366 | biostudies-arrayexpress
TranscriptomicsEarly pig response to experimental infection with Actinobacillus pleuropneomuniae
The objective of this study was to identify porcine genes which expression was affected by experimental infection with A. pleuropneumoniae within 24 hours after experimental challenge. Microarray experiments were conducted to reveal genes being significantly differentially expressed in infected vers...
ORGANISM(S): Sus scrofa 
2010-06-11 | E-GEOD-4577 | biostudies-arrayexpress
TranscriptomicsIs Increased Sinusoidal Flow in the Liver Remnant the primary Stimulus to Regeneration after partial Hepatectomy
The impact of portal arterialization on the liver parenchyma was studied in a series of six pigs with aortoportal shunting of liver segments II, III and IV (and 6 sham animals). Gene expression in the arterialized segments was compared to expression in sham animals. Primary endpoints were gene expre...
ORGANISM(S): Sus scrofa 
2010-05-07 | E-GEOD-13683 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of mouse lung tissue exposed to two multiwalled carbon nanotubes (NRCWE-26 and NM-401)
Multi-walled carbon nanotubes (MWCNTs) are extensively produced and used in composite materials and electronic applications, thus increasing risk of worker and consumer exposure. MWCNTs are an inhomogeneous group of nanomaterials that exist in various lengths, shapes and with different metal composi...
ORGANISM(S): Mus musculus 
2015-02-18 | E-GEOD-55286 | biostudies-arrayexpress
UnknownImpaired Abcb1a function and red meat in a translational colitis mouse model induces inflammation and alters microbiota composition.
Not available
S-EPMC10425965 | biostudies-literature
UnknownGermline and somatic mutations in histologically atypical congenital hyperinsulinism.
Not available
S-EPMC12812534 | biostudies-literature
UnknownEffect of Spironolactone on Kidney Function in Kidney Transplant Recipients (the SPIREN trial): A Randomized Placebo-Controlled Clinical Trial.
Not available
S-EPMC11168825 | biostudies-literature
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