Sort   by:  
 Page size 
TranscriptomicsRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Acute Pten loss initiates prostate tumorigenesis characterized by cellular senescence response. Senescent cells secrete a variety of pro inflammatory factors in the tumor microenvironment, which can support the survival, outgrowth and migration of tumor cells. Here we examine cytokines and cytokines...
ORGANISM(S): Mus musculus 
2020-10-09 | E-MTAB-9624 | biostudies-arrayexpress
ProteomicsAn Integrated Proteomic Portrait of Prostate Cancer Progression
Cancer forms a local tumor that subsequently metastasizes to distant organs. In prostate cancer, the latter part of the trajectory is influenced by the inhibition of the androgen receptor (AR). The study of proteomic changes along disease progression may reveal insights into how prostate cancer evol...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2024-10-30 | MSV000096252 | MassIVE
TranscriptomicsSingle cell sequencing analysis of senescence in Mus musculus prostate cancer models
Acute Pten loss initiates prostate tumorigenesis characterized by cellular senescence response. Here we examine the cellular senescence response in epithelial individual cells, by single-cell RNA sequencing (scRNAseq) in Ptenpc-/- and Ptenpc-/-; Timp1-/- GEMMs. ScRNAseq analysis determines a cluste...
ORGANISM(S): Mus musculus 
2020-10-09 | E-MTAB-9578 | biostudies-arrayexpress
Sort   by:  
 Page size