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TranscriptomicsExamination of mRNA decay rate in mouse embryonic fibroblasts
The CCR4-NOT dedadenylase complex is essential for mRNA decay and various biological events.To understand roles of the complex in mouse embryonic fibroblasts, we compared mRNA half-lives between control and Cnot complex-deficient mouse embryonic fibroblasts
ORGANISM(S): Mus musculus 
2020-01-29 | E-MTAB-8287 | biostudies-arrayexpress
ProteomicsFunctional analysis of CNOT3 in pancreatic beta cells
Pancreatic β-cells are responsible for production and secretion of insulin in response to increasing blood glucose levels. Therefore, defects in pancreatic β-cell function lead to hyperglycemia and diabetes mellitus. Understanding the molecular mechanisms governing β cell function is crucial for dev...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-31 | PXD018403 | Pride
Mouse Islets 
TranscriptomicsRNA-seq of mouse islets from Ins1-cre driven Cnot3 KO and control islets
The CCR4-NOT dedadenylase complex is essential for mRNA decay and various biological events.To understand roles of the complex in pancreatic beta cells, we compared global gene expression in Ins1-cre driven Cnot3 KO and control islets. Cnot3 is an important subunit of the complex and its knockout af...
ORGANISM(S): Mus musculus 
2020-08-29 | E-MTAB-8729 | biostudies-arrayexpress
UnknownGlobal hospital-based disease management of acute diverticulitis: a prospective, international cohort study.
Not available
S-EPMC12512976 | biostudies-literature
UnknownGlobal anaesthesia practice using inguinal hernia surgery as a tracer condition: a secondary analysis of an international prospective cohort study.
Not available
S-EPMC12519944 | biostudies-literature
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