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TranscriptomicsRNA-seq analysis of add-back rescued TALEN-mediated LATS2 knockout HeLa-S3 cells
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-66388 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of TALEN-mediated LATS2 knockout HeLa-S3 cells
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-63537 | biostudies-arrayexpress
TranscriptomicsLATS2 regulates repressive epigenetic integrity via regulation of Polycomb repressive complex 2
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-63538 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of TALEN-mediated LATS2 knockout HeLa-S3 cells
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-63534 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of HeLa-S3 cells treated with siRNAs targeting LATS1 and/or LATS2
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-63533 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of mouse embryonic fibroblasts upon contact inhibition
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Mus musculus 
2016-07-26 | E-GEOD-63535 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of Lats2 deficient mouse embryonic fibroblasts
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Mus musculus 
2016-07-26 | E-GEOD-63536 | biostudies-arrayexpress
TranscriptomicsmiRNA array profiling of Lats2 deficient mouse embryonic fibroblasts
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Mus musculus 
2016-07-26 | E-GEOD-63532 | biostudies-arrayexpress
ProteomicsProximity biotinylation of iNKT cells expressing TurboID-Ikaros with or without TCR stimulation
Ikaros cDNA fused to TurboID was cloned into a retroviral vector and transfected into Phoenix retrovirus packaging cells using PEI MAX (Polysceinces). Culture supernatant containing retroviruses was used for infection into DN32.D3 cells. Cells were cultured in 10%FBS/DMEM which does not contain biot...
ORGANISM(S): Mus Musculus (mouse) 
2025-09-09 | PXD059289 | JPOST Repository
GenomicsGenome-wide maps of chromatin state in LATS2-knockout HeLa-S3 cell
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-64072 | biostudies-arrayexpress
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