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GenomicsMapping polycomb complexes in human and mouse embryonic stem cells
In embryonic stem (ES) cells, bivalent chromatin domains with overlapping repressive (H3 lysine 27 tri-methylation) and activating (H3 lysine 4 tri-methylation) histone modifications mark the promoters of more than 2000 genes. To gain insight into the structure and function of bivalent domains, we m...
ORGANISM(S): Mus musculus 
2008-11-01 | E-GEOD-13084 | biostudies-arrayexpress
ProteomicsLIS1 RNA binding orchestartes the mechanosensitive properties of embryonic stem cells in AGO2 dependent and independent ways.
LIS1 immunoprecipitation in nuclear and cytoplasmic fractions of LIS1 Floxed/-, OE and WT embryonic stem cells. To identify AGO2 dependent and independent interactions LIS1 was immunoprecipitated in AGO1-4 knockout and doxycycline induced AGO2 mouse embryonic stem cells.
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD033150 | Pride
Oe Dox.ago2 Ago1-4 ko Nuclear and cytoplasmic fractions Flox/- Wt Mouse embyonic stem cells Lis1 ip 
TranscriptomicsAnalysis of cisplatin treated mouse ES cells
mouse embyonic stem cells/ cisplatin
ORGANISM(S): mus musculus 
2013-01-22 | E-MTAB-1429 | biostudies-arrayexpress
TranscriptomicsAsh1 ChIP-chip data from murine Embyonic Stem cells
Ash1 is a Trithorax Group (TrxG) protein with histone methyl transferase activity that is associated with gene activation. Here we use ChIP-chip to determine the occupancy of Ash1 at promoters in murine embryonic stem cells. This dataset includes singlet ChIP-chip data targeting Ash1 in murine Em...
ORGANISM(S): Mus musculus 
2010-05-14 | E-GEOD-20063 | biostudies-arrayexpress
GenomicsMapping polycomb complexes in human and mouse embryonic stem cells
Mapping polycomb complexes in human and mouse embryonic stem cells
PRJNA110911 | ENA
TranscriptomicsExpression data from mouse embyonic stem cell, neural progenitor and neuron
The effect of HMGN1 protein on gene expression of mouse ESC, NP and Neurons were investigated by comparing the transcriptome between Hmgn1+/+ and Hmgn1 -/- cells. three cell types, two genotypes, three reps per sample type
ORGANISM(S): Mus musculus 
2013-02-09 | E-GEOD-44175 | biostudies-arrayexpress
GenomicsExpression profile of mouse embryonic stem cells upon knockdown or overexpression of YAP
Expression profile of mouse embryonic stem cells upon knockdown or overexpression of YAP
PRJNA662512 | ENA
TranscriptomicsExpression profile of mouse embryonic stem cells upon knockdown or overexpression of YAP
We looked at the expression profiles of embyonic stem cells (ESCs) 48 hours after YAP siRNAs transfection, to knockdown YAP expression, or after pCAG-YAP transfection, to over-express YAP protein. Total RNA was isolated from three independent experiments and analyzed by RNA-seq.
ORGANISM(S): Mus musculus 
2020-12-08 | GSE157706 | GEO
TranscriptomicsGene expression in mouse embyonic cardiomyocytes, fibroblasts and adult cardiac fibroblasts
Growth and expansion of ventricular chambers is essential during cardiogenesis and is achieved by proliferation of cardiac progenitors that are not fully differentiated. Disruption of this process can lead to prenatal lethality. In contrast, adult cardiomyocytes achieve growth through hypertrophy ra...
ORGANISM(S): Mus musculus 
2009-01-14 | E-GEOD-14412 | biostudies-arrayexpress
GenomicsMus musculus
Expression data from mouse embyonic stem cell, neural progenitor and neuron
PRJNA188957 | ENA
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