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MetabolomicsInfluence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome
Although the gut microbiome plays important roles in host physiology, health and disease, we lack understanding of the complex interplay between host genetics and early life environment on the microbial and metabolic composition of the gut. We used the genetically diverse Collaborative Cross mouse s...
2016-10-05 | MTBLS345 | MetaboLights
MetabolomicsLong-lasting effects of oral polysaccharides on chemotherapy efficacy via alteration of the gut microbiota in a mouse model

Gemcitabine always has a short-term immune effect, and we consider using oral polysaccharides to lengthen its immune effect by modulating gut microbiotas. To verify this, we built a breast cancer mice model in situ, oral polysaccharides and a low-dose of Gemcitabine were administrated, ...

2025-06-14 | MTBLS12563 | MetaboLights
MetabolomicsAn overlooked prebiotic: beneficial effect of dietary nucleotide supplementation on gut microbiota and metabolites in senescence-accelerated mouse prone-8 mice
Nucleotides (NTs) are regulatory factors in many biological processes and play important roles in the growth, development, and metabolism of living organisms. We used senescence-accelerated mouse prone-8 (SAMP8) to investigate the effects of NTs on the gut microbiota and metabolites. And the promoti...
2022-03-21 | MTBLS4012 | MetaboLights
MetabolomicsHarnessing a Germ-Free Mouse Gut Bioreactor for Directed Evolution of Probiotics to Combat NAFLD

The data uploaded in this study were obtained from an interventional experiment in which non-alcoholic fatty liver disease (NAFLD) model mice were treated with either the original or adapted bacterial strains, followed by fecal sample collection and targeted bile acid metabolomic analysis.

2026-01-20 | MTBLS13718 | MetaboLights
ProteomicsMouse gut metaproteome - MetaPro-IQ: a universal metaproteomic approach to studying human and mouse gut microbiota
The mouse stool samples were collected from different diets fed mice and bacterial cells were harvest for metaproteomic analysis for understanding the role ofdiet on gut microbiota.
ORGANISM(S): mouse gut metagenome 
2016-07-05 | PXD003527 | Pride
Mouse Gut microbiota Metaproteomics Lc-ms/ms 
MetabolomicsBile acid analysis of the germ free mouse gut
Not available
ORGANISM(S): Mus musculus 
ST000831 | MetabolomicsWorkbench
ProteomicsMetaproteomic analysis of mouse gut microbiota in the early life: taxonomic, functional and quantitative analysis to evaluate breastfeeding modulation
Metaproteomic analysis of mouse gut microbiota in the early life: taxonomic, functional and quantitative analysis to evaluate breastfeeding modulation
ORGANISM(S): Bacteria (ncbitaxon:2) Mus Musculus (ncbitaxon:10090) 
2018-07-22 | MSV000082651 | MassIVE
MetabolomicsGut microbiome dysbiosis drives metabolic dysfunction in Familial dysautonomia
Familial dysautonomia (FD) is a rare genetic neurologic disorder caused by impaired neuronal development and progressive degeneration of both the peripheral and central nervous systems. FD is monogenic, with >99.4% of patients sharing an identical point mutation in the elongator acetyltransferase co...
2022-12-06 | MTBLS5138 | MetaboLights
TranscriptomicsSingle-cell transcriptomics of mouse gut
Single-cell transcriptomics of Mouse gut - colon and small intestine
ORGANISM(S): Mus musculus 
2024-11-19 | E-MTAB-13281 | biostudies-arrayexpress
TranscriptomicsThe impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. (COPRO-Seq)
Understanding how the human gut microbiota and host are impacted by probiotic bacterial strains requires carefully controlled studies in humans, and in mouse models of the gut ecosystem where potentially confounding variables that are difficult to control in humans can be constrained. Therefore, we ...
ORGANISM(S): Bacteria 
2011-11-01 | E-GEOD-31943 | biostudies-arrayexpress
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