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ProteomicsHost-centric proteomics of stool
Soluble extra-cellular proteins and peptides from human and mouse stool were fractionated on a C-4 solid phase extraction cartidge, trypsin digested, C-18 clean up and identified with MS/MS on a LTQ-Velos Orbitrap. Data processing: The readRAW program was used to generate peak lists from the origina...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2013-10-16 | PXD000240 | Pride
Host response Ms/ms Proteomics Gut microbiome Mass spectrometry 
ProteomicsHost-centric proteomics of stool, part 2 of 2
Soluble extra-cellular proteins and peptides from human and mouse stool were fractionated on a C-4 solid phase extraction cartidge, trypsin digested, C-18 clean up and identified with MS/MS on a LTQ-Velos Orbitrap. Data processing: The readRAW program was used to generate peak lists from the origina...
ORGANISM(S): Homo sapiens (Human) 
2013-10-16 | PXD000506 | Pride
Host response Ms/ms Proteomics Gut microbiome Mass spectrometry 
ProteomicsThe effect of microbial colonization on the host proteome varies by gastrointestinal location
Endogenous intestinal microbiota have wide-ranging and largely uncharacterized effects on host physiology. Here, we used reverse-phase liquid chromatography-coupled tandem mass spectrometry to define the mouse intestinal proteome in the stomach, jejunum, ileum, cecum, and proximal colon under three ...
ORGANISM(S): Mus musculus (Mouse) 
2015-11-25 | PXD002838 | Pride
Mouse gut microbiome host-centric proteomics 
ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases:Streptomycin plus Salmonella
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003152 | Pride
Inflammation Gut Antibiotic Mouse Pathogen Microbiome 
ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases:Fecal Transplant
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003170 | Pride
Mouse Fecal transplant Gut microbiome Antibiotic C difficile 
ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases: Clindamycin
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003168 | Pride
Mouse Fecal transplant Gut microbiome Antibiotic C difficile 
ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases:Control for Cln, C. diff, Fecal Transplant
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003167 | Pride
Mouse Fecal transplant Gut microbiome Antibiotic C difficile 
ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases:C. difficile infection
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003169 | Pride
Mouse Fecal transplant Gut microbiome Antibiotic C difficile 
ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases: DSS
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003171 | Pride
Mouse Fecal transplant Gut microbiome Antibiotic C difficile 
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