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ProteomicsNogo-B co-IP-MS experiment in mouse liver and pancreas
Co-immunoprecipitation with either rabbit normal IgG or anti-Nogo-B antibody followed by mass spectrometry (co-IP-MS) in the liver and pancreas of wild-type C57BL/6J mice.
ORGANISM(S): Mus musculus (Mouse) 
2024-07-27 | PXD046104 | Pride
Mouse liver and pancreas 
TranscriptomicsLRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function [RNA-Seq]
Two separate pools of three Flox or two Lrh1t-/- pancreas RNA preparations was subjected to the Illumina RNA-seq protocol. Examination of mRNA levels in induced Lrh1 pancreas knockout and wild-type mice.
ORGANISM(S): Mus musculus 
2011-11-30 | E-GEOD-34030 | biostudies-arrayexpress
GenomicsLRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function [ChIP-Seq]
We have determined the cistrome and transcriptome for the nuclear receptor liver receptor homolog-1 (LRH-1) in the exocrine pancreas. Chromatin immunoprecipitation (ChIP)-seq and RNA-seq analyses reveal that LRH-1 directly induces expression of genes encoding digestive enzymes and secretory and mit...
ORGANISM(S): Mus musculus 
2011-12-09 | E-GEOD-34295 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse pancreas in a developmental time series
Study to evaluate the expression of pancreas-specific genes at different developmental time points.
ORGANISM(S): Mus musculus 
2006-06-22 | E-CBIL-12 | biostudies-arrayexpress
TranscriptomicsRNA-Seq profiling unveils a non-canonical Wnt signalling signature in pancreas versus liver fate decision
Understanding how distinct cell types arise from common multipotent progenitor cells is a major quest in stem cell biology. This knowledge will aid in the targeted differentiation and growth of stem cells, but also in the discovery of the basis of cellular plasticity and of how tissue programming ca...
ORGANISM(S): Mus musculus 
2013-09-11 | E-GEOD-40823 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse pancreas at embryonic days 14.5 and 16.5 from animals lacking beta-catenin, a mediator of Wnt signaling and a component of the cadherin-catenin epithelial adhesion complex
Beta-catenin is an essential mediator of canonical Wnt signaling and a central component of the cadherin-catenin epithelial adhesion complex. Dysregulation of beta-catenin expression has been described in pancreatic neoplasia. Newly published studies have suggested that beta-catenin is critical for ...
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-7430 | biostudies-arrayexpress
GenomicsPtf1a and RbpjL ChIP-seq in mouse pancreas
Ptf1a and RbpjL form a complex. We wanted to identify genes that are regulated by the complex and distinguish those possibly regulated independently by Ptf1a and RbpjL in mouse pancreas using ChIP-seq technology. Chromatin Immunoprecipitations (ChIPs) for Ptf1a and RbpjL were performed with a number...
ORGANISM(S): Mus musculus 
2014-12-23 | E-MTAB-3197 | biostudies-arrayexpress
TranscriptomicsEffects of low and high doses of bisphenol A on mouse liver transcriptome
Bisphenol A (BPA) is used in the plastic industry as the monomer of polycarbonates and epoxy resins. Heat and changes in pH conditions lead to its leakage from the plastics in which it is incorporated. This largely contributes to the widespread exposure of the general population to this environmenta...
ORGANISM(S): Mus musculus 
2011-09-20 | E-GEOD-26728 | biostudies-arrayexpress
GenomicsMaternal Nutrition Induces Pervasive Gene Expression Changes but no Detectable DNA Methylation Differences in the Liver of Adult Offspring [selected loci]
Aims: Epidemiological and animal studies have shown that maternal diet can influence metabolism in adult offspring. However, the molecular mechanisms underlying these changes remain poorly understood. Here, we aim to explore phenotypes induced by maternal obesity in a mouse model and examine gene ex...
ORGANISM(S): Mus musculus 
2014-03-04 | E-GEOD-52267 | biostudies-arrayexpress
GenomicsMaternal Nutrition Induces Pervasive Gene Expression Changes but no Detectable DNA Methylation Differences in the Liver of Adult Offspring [RRBS]
Aims: Epidemiological and animal studies have shown that maternal diet can influence metabolism in adult offspring. However, the molecular mechanisms underlying these changes remain poorly understood. Here, we aim to explore phenotypes induced by maternal obesity in a mouse model and examine gene ex...
ORGANISM(S): Mus musculus 
2014-03-04 | E-GEOD-52266 | biostudies-arrayexpress
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