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MetabolomicsProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis

Genes are pleiotropic and getting a better knowledge of their function requires a comprehensive characterization of their mutants. Here, we generated multi-level data combining phenomic, proteomic and metabolomic acquisitions from plasma and liver tissues of two C57BL/6 N mouse models lacking the...

2021-09-01 | MTBLS1903 | MetaboLights
MetabolomicsUntargeted Metabolomics Reveals Molecular Effects of Ketogenic Diet on Healthy and Tumor Xenograft Mouse Models
The application of ketogenic diet (KD) (high fat/low carbohydrate/adequate protein) as an auxiliary cancer therapy is a field of growing attention. KD provides sufficient energy supply for healthy cells, while possibly impairing energy production in highly glycolytic tumor cells. Moreover, KD regula...
2019-10-08 | MTBLS1066 | MetaboLights
MetabolomicsTargeted polyamine metabolomics of ATP13A4-deficient cellular and mouse models

ATP13A4 is a polyamine transporter enriched in astrocytes that regulates extracellular polyamine homeostasis. This study contains targeted LC-MS/MS metabolomics data from ATP13A4-deficient cellular and mouse models, including C8-D1A astrocytic cells, astrocyte-conditioned medium, mouse cortex, pl...

2026-06-10 | MTBLS14724 | MetaboLights
MetabolomicsComparative Analysis of Host Metabolic Alterations in Murine Malaria Models with Uncomplicated or Severe Malaria

Malaria varies in severity, with complications ranging from uncomplicated to severe malaria. Severe malaria could be attributed to peripheral hyperparasitemia or cerebral malaria. The metabolic interactions between the host and Plasmodium species are yet to be understood during these inf...

2022-09-14 | MTBLS4387 | MetaboLights
MetabolomicsMeasuring NEFA concentrations in insulin resistant and insulin deficient mouse tissue models
Not available
ORGANISM(S): Mus musculus 
ST000521 | MetabolomicsWorkbench
MetabolomicsMeasuring ceramide concentrations in insulin resistant and insulin deficient mouse tissue models
Not available
ORGANISM(S): Mus musculus 
ST000518 | MetabolomicsWorkbench
MetabolomicsMeasuring acylcarnitine concentrations in insulin resistant and insulin deficient mouse tissue models
Not available
ORGANISM(S): Mus musculus 
ST000517 | MetabolomicsWorkbench
MetabolomicsMeasuring TCA cycle concentrations in insulin resistant and insulin deficient mouse tissue models
Not available
ORGANISM(S): Mus musculus 
ST000520 | MetabolomicsWorkbench
MetabolomicsMeasuring amino acid metabolites in insulin resistant and insulin deficient mouse tissue models
Not available
ORGANISM(S): Mus musculus 
ST000516 | MetabolomicsWorkbench
MetabolomicsSafety and efficacy analysis of in vivo lentiviral gene therapy in pre-clinical ARC syndrome models
Safety and efficacy analysis of in vivo lentiviral gene therapy in pre-clinical ARC syndrome models
2026-04-29 | MTBLS14408 | MetaboLights
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