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TranscriptomicsTranscription profiling of preimplantation mouse embryos to study the requirement of the MAP kinase signaling pathway for preimplantation development.
We examined expression profiles of genes that could be regulated by the MAPK pathways during mouse preimplantation development. We used Affymetrix GeneChips for microarray analysis, and three independent experiments were carried out. 8-cell stage embryos were treated or untreated with MAPK inhibit...
ORGANISM(S): Mus musculus 
2007-09-25 | E-GEOD-2229 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of preimplantation mouse embryo development
Preimplantation mouse embryo development study on Affymetrix MOE430A. Zeng et al (2004) Dev Biol 272:483-496.
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-1744 | biostudies-arrayexpress
ProteomicsComparative proteomic landscapes provide insights into mammalian preimplantation development and failure
Understanding mammalian preimplantation development, particularly in humans, at the proteomic level remains limited. Here, we applied our comprehensive solution of ultrasensitive proteomic technology to measure the proteomic profiles of oocytes and early embryos and identified nearly 8,000 proteins ...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-05 | PXD054371 | Pride
Protein turnover Mouse preimplantation development Multi-omics analysis Zygotic genome activation (zga) Ultrasensitive proteomics Cross species analysis 
ProteomicsComparative proteomic landscapes provide insights into mammalian preimplantation development
Proteins play a crucial role in the central dogma as the end product of gene expression. However, a deep proteomic landscape is still the missing puzzle piece of the comprehensive understanding of mammalian preimplantation development. Here, using our recently developed Comprehensive Solution of Ult...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-27 | PXD043363 | Pride
Protein turnover Mouse preimplantation development Multi-omics analysis Zygotic genome activation (zga) Ultrasensitive proteomics Cross species analysis 
TranscriptomicsTranscription profiling of mouse embryo development
Preimplantation mouse embryo development on Affymetrix MOE430B. Zeng et al (2004) Dev Biol 272:483-496.
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-1745 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse preimplantation development
Preimplantation development is a crucial step for successful implantation and pregnancy. Although both compaction and blastocyst formation have been extensively studied, mechanisms regulating early cell division stages before compaction have remained unclear. Here, we show that ERK MAP kinase funct...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7309 | biostudies-arrayexpress
ProteomicsProteome analysis of mouse oocytes and pre-implantation embryos
Mouse oocytes and embryos from the germinal vesicle (GV) stage to the blastocyst stage were collected and treated with acidic Tyrode’s solution to remove the zona pellucida. We used 42.5 oocytes or embryos per sample at each developmental stage and identified the proteome during mouse pre-implantati...
ORGANISM(S): Mus Musculus (mouse) 
2025-05-22 | PXD059122 | JPOST Repository
TranscriptomicsTranscription profiling of mouse embryo to assess gene expression during preimplantation mouse development
Studies using low-resolution methods to assess gene expression during preimplantation mouse development indicate that changes in gene expression either precede or occur concomitantly with the major morphological transitions, that is, conversion of the oocyte to totipotent 2-cell blastomeres, compact...
ORGANISM(S): Mus musculus 
2007-10-23 | E-GEOD-1749 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryo development U74Av2
Preimplantation mouse embryo development study on Affymetrix U74Av2. Zeng et al Dev Biol (2004) 272:483-496.
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-1391 | biostudies-arrayexpress
TranscriptomicsThe absence of a Ca(2+) signal during mouse egg activation can affect development and gene expression patterns
The absence of a Ca(2+) signal during mouse egg activation can affect parthenogenetic preimplantation development, gene expression patterns, and blastocyst quality. Gene expression pattern of parthenogenetic mouse embryos by cycloheximide or Sr2+. Keywords: development or differentiation design Gene...
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-5077 | biostudies-arrayexpress
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