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Proteomicsmouse adult testis ADAD2 Immuno-precipitation and mass-spectrometry (IP-MS)
To explore the mechanism of pachytene pirna biogenesis, we employed a proteomics approach using flag-tagged adad2 transgenic mice expressed fully functional N-terminal epitope-tagged HA-ADAD2 and performed anti-FLAG immunoprecipitation coupled with quantitative mass spectrometry (IP-MS) from testis ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-14 | PXD034437 | Pride
Mouse testis adad2 
GenomicsRNA sequencing of late juvenile whole mouse wildtype and Adad2 mutant testis
RNA sequencing of late juvenile whole mouse wildtype and Adad2 mutant testis
PRJNA633504 | ENA
TranscriptomicsRNA sequencing of late juvenile whole mouse wildtype and Adad2 mutant testis
Adenosine-to-inosine RNA editing, a fundamental RNA modification, is regulated by adenosine deaminase (AD) domain containing proteins. Within the testis, RNA editing is catalyzed by ADARB1 and is regulated in a cell-type dependent manner. This study examined the role of two testis-specific AD domain...
ORGANISM(S): Mus musculus 
2020-07-01 | GSE150755 | GEO
UnknownADAD1 and ADAD2, testis-specific adenosine deaminase domain-containing proteins, are required for male fertility.
Not available
S-EPMC7360552 | biostudies-literature
GenomicsADAD2 facilitates piRNA biogenesis and spermiogenesis in mice
ADAD2 facilitates piRNA biogenesis and spermiogenesis in mice
PRJNA863269 | ENA
Proteomicsmouse adult testis RNF17 Immuno-precipitation and mass-spectrometry (IP-MS)
To explore the mechanism of pachytene pirna biogenesis, we performed anti-RNF17 immunoprecipitation coupled with quantitative mass spectrometry (IP-MS) from testis extracts of adult mice.
ORGANISM(S): Mus musculus (Mouse) 
2023-03-14 | PXD034463 | Pride
Mouse testis rnf17 
UnknownADAD2 functions in spermiogenesis and piRNA biogenesis in mice.
Not available
S-EPMC10073342 | biostudies-literature
UnknownWhole exome sequencing analysis of 167 men with primary infertility.
Not available
S-EPMC11391607 | biostudies-literature
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