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MetabolomicsLactobacillus plantarum MR1 alleviates high-carbohydrate diet-induced oxidative stress and liver lipid deposition via upregulating uridine synthesis
The overconsumption of carbohydrates induces oxidative stress and lipid accumulation in the liver, which can be alleviated by modulation of intestinal microbiota; however, the underlying mechanism remains unclear. Here, we demonstrated that a strain affiliated with Lactobacillus plantarum (de...
2024-01-16 | MTBLS4262 | MetaboLights
TranscriptomicsSingle cell RNA-seq of metabolite specific T-cells (MR1-restricted) from adult mouse thymus
Mucosal-Associated Invariant T cells (MAIT cells) have a unique specificity for the microbial metabolite 5-OP-RU presented by the non-classical presentation molecule MR1. Upon activation, they release cytotoxic mediators and engage an antimicrobial activity. As a subset of T lymphocytes, MAIT develo...
ORGANISM(S): Mus musculus 
2019-07-01 | E-MTAB-7704 | biostudies-arrayexpress
GenomicsBurkholderia sp. MR1
Burkholderia sp. MR1 Genome sequencing and assembly
PRJNA269162 | ENA
GenomicsStaphylococcus aureus subsp. aureus MR1
Staphylococcus aureus subsp. aureus MR1 Genome sequencing
PRJNA40705 | ENA
ProteomicsCo-immunoprecipitation and proteomic analysis of Major Histocompatibility Complex Class I-related (MR1) mutants
Identification of cellular proteins mediating presentation of bacterial antigens by the MHC I-related protein MR1. MR1 mutant proteins that differ in their capacity to present antigens from different sources were immunoprecipitated and their interacting proteins were compared to identify candidate p...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD063725 | Pride
Lcms Mr1 
ProteomicsCo-immunoprecipitation and proteomic analysis of Major Histocompatibility Complex Class I-related (MR1) mutants
Identification of cellular proteins mediating presentation of bacterial antigens by the MHC I-related protein MR1. MR1 mutant proteins that differ in their capacity to present antigens from different sources were immunoprecipitated and their interacting proteins were compared to identify candidate p...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD062277 | Pride
Co-immunoprecipitation Antigen presentation Mr1 Endosomal trafficking 
TranscriptomicsRNAseq analysis of colon and ileum tissue from naive wild type, MR1-/- and IL-17A-/- mice
Determination of differentially expressed genes in the proximal colon and distal ileum tissue in MR1 and IL-17A deficiency at steady-state. Tissue from naïve mice was harvested, total RNA extracted and subjected to RNASeq analysis.
ORGANISM(S): Mus musculus 
2018-03-31 | E-MTAB-6547 | biostudies-arrayexpress
ProteomicsEndoplasmic Reticulum Chaperones Stabilize Ligand-Receptive MR1 molecules for Efficient Presentation of Metabolite Antigens
Quantitative MS analysis of MR1 GFP immunoprecipates to identify steady-state binding partnets.
ORGANISM(S): Homo sapiens (Human) 
2020-09-16 | PXD014585 | Pride
Mr1 Mait cells Mhc Label-free ms 
GenomicsAcinetobacter johnsonii strain:MR1
Acinetobacter johnsonii strain:MR1 Genome sequencing
PRJNA746049 | ENA
GenomicsMetschnikowia reukaufii strain:MR1
Metschnikowia reukaufii MR1 transcriptome - fukami770 MR1_high
PRJNA652414 | ENA
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