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xref:PubMed:40240347
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Structural study of human MRE11-RAD50-NBS1 (MRN) complex by crosslinking mass spectrometry
A chemical crosslinking-mass spectrometry (CX-MS) experiment was performed to study the structure of the human MRN complex in the presence of ATM and DNA.
ORGANISM(S):
Homo sapiens (Human)
2025-08-13
|
PXD067324
|
Pride
Cx-ms
Mrn complex
Cite
DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end-joining
DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end-joining
PRJNA701448
|
ENA
Cite
hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity.
Not available
S-EPMC3089470
|
biostudies-literature
Cite
The Multiple Faces of the MRN Complex: Roles in Medulloblastoma and Beyond.
Not available
S-EPMC10377613
|
biostudies-literature
Cite
DNA Repair Mechanisms, Protein Interactions and Therapeutic Targeting of the MRN Complex.
Not available
S-EPMC9656488
|
biostudies-literature
Cite
Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection.
Not available
S-EPMC2666027
|
biostudies-literature
Cite
A role for the MRN complex in ATR activation via TOPBP1 recruitment.
Not available
S-EPMC3669687
|
biostudies-literature
Cite
Mitosis-specific MRN complex promotes a mitotic signaling cascade to regulate spindle dynamics and chromosome segregation.
Not available
S-EPMC6205471
|
biostudies-literature
Cite
The MRN complex and topoisomerase IIIa-RMI1/2 synchronize DNA resection motor proteins.
Not available
S-EPMC9971906
|
biostudies-literature
Cite
The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress.
Not available
S-EPMC4716299
|
biostudies-literature
Cite
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