Sort   by:  
 Page size 
TranscriptomicsGenome wide expression profiling of mesenchymal stem cells of fetal and adult origin and dermal fibroblasts
In animal models and human trials, intramyocardial injection of adult bone-marrow derived mesenchymal stem cells (BM-MSC) provides beneficial effects in failing hearts. These effects are mainly mediated through paracrine mechanisms. Mesenchymal stem cells of fetal origin (hAMC) can be isolated from ...
ORGANISM(S): Homo sapiens 
2015-06-15 | E-GEOD-61153 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human MSC isolated from human bone marrow aspirates differentiated to chondrocytes with BMP2 or TGFbeta-3, vs undifferentiated MSC sampled at multiple time points
Human mesenchymal stem cells (MSC) display a high potential for the development of novel treatment strategies for cartilage repair. However, the pathways involved in their differentiation to functional and non hypertrophic chondrocytes remain largely unknown, despite the work on embryologic developm...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-10315 | biostudies-arrayexpress
ProteomicsProteome characterization of mesenchymal stem cells and exosomes
Proteome characterization of mesenchymal stem cells (MSC) and exosomes. MSCs were cultured in normoxic, hypoxic and in presence of FBS. Exosomes were prepared from normoxic and hypoxic conditions.
ORGANISM(S): Homo Sapiens (human) 
2021-04-27 | PXD025584 | JPOST Repository
ProteomicsProteome analysis of adipose-derived stem cells cultured under clinically relevant conditions in a wound healing perspective
There is a large body of evidence supporting the beneficial role of adipose-derived stem cells (ASCs) in tissue repair and regeneration. These effects appear to be mainly mediated by paracrine signaling pathways and enhanced during hypoxia. Mass spectrometry (MS) represents a valuable tool for prote...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080858 | MassIVE
TranscriptomicsEffect of IL-1M-NM-2 on mesenchymal stem cells
Mesenchymal stem cells are often transplanted in inflammatory environments and they are able to survive and modulate host immune responses through mechanism poorly understood. In this paper we analyzed biological responses of MSC in response IL-1M-NM-2 as a representative inflammatory mediator. Micr...
ORGANISM(S): Homo sapiens 
2012-06-21 | E-GEOD-33755 | biostudies-arrayexpress
UnknownGinsenoside RG1 enhances the paracrine effects of bone marrow-derived mesenchymal stem cells on radiation induced intestinal injury.
Not available
S-EPMC7835034 | biostudies-literature
TranscriptomicsHuman Mesenchymal Stem Cells Exploit the Immune Response Mediating Chemokines to Impact the Phenotype of Glioblastoma
Four human mesenchymal stem cells (hMSC) clones (MSC-1, MSC-2, MSC-3, MSC-4) and three different glioblastoma multiformae (GBM) cell lines (U87-MG, U251, U373) were used to study their mutual paracrine interactions in the indirect co-cultures compared to their monocultures, which were grown under th...
ORGANISM(S): Homo sapiens 
2011-12-20 | E-GEOD-26283 | biostudies-arrayexpress
TranscriptomicsHeterogeneous niche activity of ex-vivo cultured MSCs as a parameter for outcomes in MSC-based cell therapy for hematopoietic recovery
Ex-vivo expanded mesenchymal stromal cells (MSCs) are increasingly used for paracrine support of hematopoietic stem cell (HSC) regeneration, but inconsistent outcomes have been the huddle for on-going clinical trials. Here, we hypothesized that the heterogeneity in the niche activity of manufactured...
ORGANISM(S): Homo sapiens 
2016-07-25 | E-GEOD-84754 | biostudies-arrayexpress
TranscriptomicsGraphene Oxide Substrate Promotes Neurotrophic Factor Secretion and Survival of Human Schwann-Like Adipose Mesenchymal Stromal Cells - RNAseq
Mesenchymal stromal cells from adipose tissue (AD-MSCs) exhibit favourable clinical traits for autologous transplantation and can develop a ‘Schwann-like’ phenotype (sAD-MSCs) to improve peripheral nerve regeneration, where severe injuries yield insufficient recovery. However, sAD-MSCs regress witho...
ORGANISM(S): Homo sapiens 
2021-03-08 | E-MTAB-10078 | biostudies-arrayexpress
UnknownEffects of Mesenchymal Stem Cell-Derived Paracrine Signals and Their Delivery Strategies.
Not available
S-EPMC7995150 | biostudies-literature
Sort   by:  
 Page size