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We used H83M2 P element to ectopically expressed MSL2 protein in females to test if the novel formed MSL complex is the directly reason of dosage compensation Compare the MSL2 females with normal females and normal males; MSL2 males also included.
ORGANISM(S): Drosophila melanogaster 
Dosage compensation in Drosophila is an epigenetic phenomenon utilizing proteins and long non-coding RNAs (lncRNAs) for transcriptional up-regulation of the entire X-chromosome. Here, UV cross-linking followed by deep sequencing (iCLIP) show that two enzymes in the Male-Specific Lethal complex, MLE ...
ORGANISM(S): Drosophila melanogaster 
Reconstitution of MSL2 binding in vtiro
CaBl: MSL2 is an allelic dosage sensor in mammals
BlCa: MSL2 is an allelic dosage sensor in mammals
9sCa: MSL2 is an allelic dosage sensor in mammals
MSL2 cut and run profiles in S2 cell lines
CaBlCaXi: MSL2 is an allelic dosage sensor in mammals
BL6Mousei: MSL2 is an allelic dosage sensor in mammals
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